Print Print
CKS is no longer commissioned by the National Institute for Health and Clinical Excellence (NICE). NICE remains committed to providing a replacement service for CKS and is currently reviewing its options. In the meantime, although CKS content is now not being maintained, it still remains relevant and will continue to be made available. CKS content was generated under a programme of topic creation and update. To check if the topic you are viewing is current or out of date, please refer to the topic publication details by clicking on the 'How up-to-date is this topic?' link in the left hand menu on individual topic pages.

Angina - stable - Management
What should I advise about sexual activity?

  • Advise the person that, if they can briskly climb up and down two flights of stairs without any symptoms of angina, sexual activity is unlikely to precipitate an episode of angina.
  • If sexual activity does precipitate an episode of angina, sublingual glyceryl trinitrate taken immediately before intercourse may help prevent subsequent attacks.
  • The concomitant use of nitrates or nicorandil with phosphodiesterase inhibitors (sildenafil, tadalafil, and vardenafil), often used in the treatment of erectile dysfunction, is contraindicated.
  • Advise people with angina who take a phosphodiesterase inhibitor that:
    • They should not use glyceryl trinitrate (GTN) for at least 24 hours before taking sildenafil or vardenafil and for at least 48 hours before taking tadalafil.
    • They should not use GTN for at least 24 hours after taking sildenafil or vardenafil and for at least 48 hours after taking tadalafil.
    • If they have an episode of angina during sexual intercourse, they must not use GTN. They should stop sexual activity and, if their pain does not resolve, they should call for an ambulance.

In depth

© NHS Institute for Innovation and Improvement