Print Print
CKS is no longer commissioned by the National Institute for Health and Clinical Excellence (NICE). NICE remains committed to providing a replacement service for CKS and is currently reviewing its options. In the meantime, although CKS content is now not being maintained, it still remains relevant and will continue to be made available. CKS content was generated under a programme of topic creation and update. To check if the topic you are viewing is current or out of date, please refer to the topic publication details by clicking on the 'How up-to-date is this topic?' link in the left hand menu on individual topic pages.

Aphthous ulcer - Management
Topical corticosteroids

  • Hydrocortisone 2.5 mg lozenges are licensed for use in aphthous ulcers [BNF 53, 2007]. Triamcinolone in an adhesive paste (Adcortyl in Orabase®) has been discontinued.
  • Encourage individuals with prodromal symptoms to apply corticosteroids at this stage. Otherwise, corticosteroids should be applied as soon as the ulcers appear [Scully et al, 2003].
  • Concerns have been raised that long-term or repeated application could cause adrenal suppression. However, there is little evidence that even some of the more potent steroids (such as fluocinonide or betamethasone) cause significant problems in this respect [Scully et al, 2002].

© NHS Institute for Innovation and Improvement