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Asthma - Management
Children and adults who need admission to hospital: How do I manage?

  • Organize urgent hospital admission.
  • Give high-flow oxygen (40–60%) with a tight-fitting mask. If pulse oximetry is available, adjust the flow rate to maintain an oxygen saturation of 94–98%.
  • Give a short-acting inhaled beta2-agonist:
    • For life-threatening asthma, give via a nebulizer, if available. Repeat every 20–30 minutes according to clinical response.
      • Ideally, nebulizers should be oxygen driven (flow rate of 6 L/min usually needed) to avoid worsening hypoxia.
    • For severe attacks, give via a nebulizer (preferred for children if available) or use a pressurized metered-dose inhaler with a large-volume spacer.
      • For an adult, give 4 puffs initially, followed by 2 puffs every 2 minutes according to response, up to 10 puffs.
      • For a child, give 2 puffs every 2 minutes according to response, up to 10 puffs.
      • Each puff should be given one at a time and inhaled with five tidal breaths. Repeat every 10–20 minutes according to clinical response.
    • For moderate attacks, use a pressurized metered-dose inhaler with a large-volume spacer.
  • Give the first dose of a course of prednisolone.
  • Monitor peak expiratory flow rate (if the person can comply) and oxygen saturation (if available) to assess response to treatment.
  • If the person does not respond to a beta2-agonist, consider continuous nebulized beta2-agonists or addition of ipratropium bromide (via a nebulizer). However, aim to get the person to hospital urgently.

In depth

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