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Atrial fibrillation - Management
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How should I review someone with established atrial fibrillation?

  • Check for ongoing symptoms (at rest or with exercise) and assess heart rate.
    • If the person is taking rate-control treatment and has persistent symptoms or a fast heart rate, consider increasing the drug dose (if they are not taking the maximum dose), combining drug treatments (if this has not already been done), or referring to a cardiologist.
    • If the person is taking rhythm-control treatment and has recurring or persistent symptoms, refer back to a cardiologist for further assessment (for example for development of persistent atrial fibrillation [AF] or failed rhythm-control treatment).
  • Assess stroke and cardiovascular disease (CVD) risk.
    • If the person is not taking warfarin, reassess risk of stroke if they develop diabetes, hypertension, or cardiovascular disease or when they reach 65 and 75 years of age.
    • If the person is taking warfarin, reassess risk of bleeding (such as risk of falling).
    • For information on how to assess CVD risk, see the CKS topic on CVD risk assessment and management.
  • Check for complications of AF and assess blood pressure.
  • Review the person's medication.
    • Check compliance, and identify and manage drug interactions and complications (such as dyspepsia with aspirin).
    • Give advice on known drug interactions and which drugs should be avoided with aspirin or warfarin (see Prescribing information).
  • Provide information on AF.
    • Provide written information (if this has not already been given).
    • Explain when to seek further medical advice (such as worsening symptoms).
    • For more information on patient education and support groups, see www.atrialfibrillation.org.uk.

In depth

What advice should I give about driving?

  • Advise the person that it is their responsibility to inform the Driver and Vehicle Licensing Agency (DVLA) of any condition that may affect their ability to drive.
  • The DVLA's medical rules regarding atrial fibrillation are:
    • For group 1 entitlement (cars, motorcycles):
      • Driving must cease if the arrhythmia has caused or is likely to cause incapacity.
      • Driving may be permitted when the underlying cause has been identified and controlled for at least 4 weeks
      • The DVLA need not be notified unless there are distracting or disabling symptoms.
    • For group 2 entitlement (lorries, buses):
      • Disqualified from driving if the arrhythmia has caused or is likely to cause incapacity.
      • Driving may be permitted when the arrhythmia is controlled for at least 3 months; the left ventricular ejection fraction is equal to or greater than 0.4; there is no other disqualifying condition.
  • The person should check with their insurer that they are still covered for driving.
  • The latest information from the DVLA regarding medical fitness to drive can be obtained at www.dvla.gov.uk/medical/ataglance.

In depth

In depth

What advice should I give about flying?

  • Advise the person that there are no flying restrictions provided they have stable atrial fibrillation which has not recently worsened or become more symptomatic.

In depth

In depth

Prescriptions

Antithrombotics

Age from 16 years onwards
Aspirin dispersible tablets: 75mg once a day
Aspirin 75mg dispersible tablets
Take one tablet once a day.
Supply 28 tablets.
Age: from 16 years onwards
NHS cost: £0.82
OTC cost: £1.66
Licensed use: yes
Aspirin dispersible tablets: 300mg once a day
Aspirin 300mg dispersible tablets
Take one tablet once a day.
Supply 28 tablets.
Age: from 16 years onwards
NHS cost: £0.27
OTC cost: £0.55
Licensed use: yes
Warfarin 1mg tablets
Warfarin 1mg tablets
Take as directed in your yellow anticoagulant booklet.
Supply 28 tablets.
Age: from 16 years onwards
NHS cost: £1.10
Licensed use: yes
Patient information: Make sure that you know which tablets to take each day. You should have an advice booklet to tell you about these tablets. Please ask the pharmacist if you are unsure.
Warfarin 3mg tablets
Warfarin 3mg tablets
Take as directed in your yellow anticoagulant booklet.
Supply 28 tablets.
Age: from 16 years onwards
NHS cost: £1.15
Licensed use: yes
Patient information: Make sure that you know which tablets to take each day. You should have an advice booklet to tell you about these tablets. Please ask the pharmacist if you are unsure.
Warfarin 5mg tablets
Warfarin 5mg tablets
Take as directed in your yellow anticoagulant booklet.
Supply 28 tablets.
Age: from 16 years onwards
NHS cost: £1.21
Licensed use: yes
Patient information: Make sure that you know which tablets to take each day. You should have an advice booklet to tell you about these tablets. Please ask the pharmacist if you are unsure.

Start beta-blocker

Age from 16 years onwards
Start atenolol tablets: 25mg once a day
Atenolol 25mg tablets
Take one tablet once a day.
Supply 28 tablets.
Age: from 16 years onwards
NHS cost: £0.82
Licensed use: yes

Start calcium-channel blocker (NOT if taking beta-blocker)

Age from 16 to 70 years
Start diltiazem tablets: 60 mg three times a day (usual start dose)
Diltiazem 60mg modified-release tablets
Take one tablet three times a day.
Supply 84 tablets.
Age: from 16 years to 70 years
NHS cost: £3.52
Licensed use: no - off-label indication
Age from 16 years onwards
Start verapamil tablets: 40 mg three times a day
Verapamil 40mg tablets
Take one tablet three times a day.
Supply 84 tablets.
Age: from 16 years onwards
NHS cost: £1.55
Licensed use: yes
Patient information: Do NOT eat or drink products containing grapefruit juice whilst taking this medicine.
Age from 70 years onwards
Start diltiazem tablets: 60 mg twice a day (elderly start dose)
Diltiazem 60mg modified-release tablets
Take one tablet twice a day.
Supply 56 tablets.
Age: from 70 years onwards
NHS cost: £2.35
Licensed use: no - off-label indication

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