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Benzodiazepine and z-drug withdrawal - Management
How should I manage withdrawal symptoms?

  • Review frequently to detect and manage problems early, and to provide encouragement and reassurance during and after drug withdrawal.
  • Manage anxiety.
    • Explain that anxiety is the most common acute withdrawal symptom.
    • Reassure that anxiety is likely to be temporary.
    • Consider slowing or suspending withdrawal until symptoms become manageable.
    • Consider additional use of non-drug treatments.
    • Adjunct drug therapy should not be routinely prescribed but may be considered:
      • Propranolol: for severe, physical symptoms of anxiety (such as palpitations, tremor, and sweating) only if other measures fail.
      • Antidepressants: only if depression or panic disorder coexist or emerge during drug withdrawal.
      • Do not prescribe antipsychotics which may aggravate withdrawal symptoms.
    • Seek specialist advice if symptoms are severe or difficult to manage.
  • Manage depression.
    • If depression emerges or coexists with withdrawal symptoms:
      • Consider suspending drug withdrawal until the depression resolves.
      • See the CKS topic on Depression for further information on the management of depression.
  • Manage insomnia.
    • Adverse effects on sleep are not likely to be a problem if drug withdrawal is slow.
    • Non-drug treatments have proved to be beneficial in managing long-term insomnia and should be considered for all people with long-term insomnia problems — see the CKS topic on Insomnia.

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