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Bites - human and animal - Management
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Scenario: Assessing a bite

How should I assess a bite?

  • Document how and when the bite occurred.
  • Examine the bite, and document its location, appearance, and any damage to underlying structures (e.g. arteries, nerves, tendons, or joints).
  • Determine whether the person is at increased risk of the wound becoming infected, either due to the nature of the bite or due to a medical condition (e.g. diabetes, immunosuppressed status).
  • Assess whether the wound is infected. The following may be present: redness, swelling, serosanguinous or purulent discharge, pain, localized cellulitis, lymphadenopathy, or fever.
  • Determine tetanus status.
  • For human bites: assess whether there is a risk of acquiring a blood-borne viral infection (e.g. hepatitis B or C, or HIV).
    • In most cases, the status of the biter will not be known, and it is often not practical to obtain a blood sample for testing. There is a higher risk of acquiring a blood-borne virus if:
      • The biter is known to be HIV positive, hepatitis B surface antigen (HBsAg) positive, or hepatitis C positive.
      • The biter is likely to be a high-risk person, such as an intravenous drug user.
    • Assess the status of the person who has been bitten:
      • Ask if they are known to be HIV positive, hepatitis B surface antigen (HBsAg) positive, or hepatitis C positive.
      • Check their vaccination status for hepatitis B.
  • It is essential to obtain an X-ray in people with the following:
    • Clenched fist injuries, to exclude the presence of teeth or dental fragments, and to rule out bone damage.
    • Crush injuries, suspected fractures, bites where a foreign body is a possibility.
  • For animal bites: assess the risk of acquiring rabies, and discuss the need for post-exposure prophylaxis urgently with the Virus Reference Department of the Health Protection Agency (telephone 020 8327 6017).

Scenario: Managing a human bite

When should I refer someone with a human bite?

  • Refer to secondary care:
    • Penetrating wounds involving arteries, joints, nerves, muscles, tendons, bones, or the central nervous system. Note: penetrating bites to the hands or feet are at particular risk of infection and serious complications.
    • Facial wounds (excluding very minor wounds).
    • Bites where there is a possibility of a foreign body (e.g. a tooth) in the wound.
    • Devitalized wounds where debridement is required.
    • Bites where the severity of the injury is difficult to assess.
    • People with severe cellulitis, or with infected bite wounds that are not responding to treatment, or who are systemically unwell.
    • People with an increased risk of infection — including those with diabetes or cirrhosis, those who are immunocompromised, and asplenic individuals (especially if they are not taking prophylactic penicillin).
    • Injuries requiring reconstructive surgery.
    • Bites to poorly vascularized areas e.g. ear cartilage/nose cartilage.
  • If adult bites have been inflicted on a child, consider child protection issues. Follow local policies for referral of children considered at risk.

In depth

How should a human bite wound be cared for initially?

  • If the wound has just occurred, encourage it to bleed, unless it is already bleeding freely.
  • Irrigate thoroughly with warm, running water.
  • Wound closure is rarely advised in primary care. For more information, see When to close a human bite wound in Detailed information.
  • Advise analgesia (paracetamol or ibuprofen) for pain relief, if required.
  • Prescribe prophylactic antibiotics for for all human bite wounds under 72 hours old, even if there is no sign of infection.
  • Consider if tetanus prophylaxis is required.
  • Where body tissue has been torn off as a result of a bite, wrap any torn off parts (e.g. part of an ear) in clean tissue and store in a plastic bag surrounded by ice for transport to hospital.
  • Seek immediate advice from a consultant in infectious diseases for anyone considered to be at risk of HIV or hepatitis B. For more information, see Managing risk of a viral infection.

In depth

How do I treat a human bite that has become infected?

  • Send pus or a deep wound swab for culture, before cleaning the wound. State on the form that the swab is from an infected human bite.
  • Treat empirically for 7 days with oral antibiotics.
  • Admit anyone who has a severe infection or who is systemically unwell.

In depth

Which antibiotic should I give to someone with a human bite?

  • For both prophylaxis and treatment of an infected human bite prescribe a 7-day course of co-amoxiclav.
  • For people who are allergic to penicillin prescribe a 7-day course of:
    • Metronidazole plus doxycycline, or
    • Metronidazole plus erythromycin, or
    • Metronidazole plus clarithromycin.

In depth

What follow-up is needed for someone who has had a human bite?

  • This follow-up advice only applies to people have not been referred to hospital.
  • If the bite wound is not infected — advise the person to check for signs of infection and if these develop to attend urgently for review.
  • If the wound is infected — review at 24 and 48 hours to ensure the infection is responding to treatment. Advise the person to attend urgently for review if the infection worsens or if they feel increasingly unwell.
  • For follow-up of people who are at high risk of a blood-borne virus, see Managing risk of a viral infection.

In depth

Prescriptions

Analgesia: use when required

Age from 1 month to 2 months
Paracetamol s/f susp: 30mg to 60mg up to three times a day
Paracetamol 120mg/5ml oral suspension paediatric sugar free
Take 1.25ml to 2.5ml every 8 hours when required for pain relief. Maximum of 3 doses in 24 hours.
Supply 100 ml.
Age: from 1 month to 2 months
NHS cost: £0.44
OTC cost: £0.78
Licensed use: no - off-label age
Ibuprofen s/f susp: 5mg/kg three to four times a day (> 5kg)
Ibuprofen 100mg/5ml oral suspension sugar free
*WEIGHT REQUIRED* Take 5mg per kg bodyweight three to four times a day when required for relief of pain. Do not exceed the stated dose.
Supply 50 ml.
Age: from 1 month to 2 months
NHS cost: £0.76
OTC cost: £1.82
Licensed use: no - off-label indication
Age from 3 to 5 months
Ibuprofen s/f susp: 50mg three times a day
Ibuprofen 100mg/5ml oral suspension sugar free
Take 2.5ml three times a day when required for pain relief. Do not exceed the stated dose.
Supply 50 ml.
Age: from 3 months to 5 months
NHS cost: £0.76
OTC cost: £1.82
Licensed use: yes
Age from 3 to 11 months
Paracetamol s/f susp: 60mg to 120mg up to four times a day
Paracetamol 120mg/5ml oral suspension paediatric sugar free
Take 2.5ml to 5ml every 4 to 6 hours when required for pain relief. Maximum of 4 doses in 24 hours.
Supply 150 ml.
Age: from 3 months to 11 months
NHS cost: £0.97
OTC cost: £2.32
Licensed use: yes
Age from 6 to 11 months
Ibuprofen s/f susp: 50mg three to four times a day
Ibuprofen 100mg/5ml oral suspension sugar free
Take 2.5ml three to four times a day when required for pain relief. Do not exceed the stated dose.
Supply 100 ml.
Age: from 6 months to 11 months
NHS cost: £1.51
OTC cost: £3.62
Licensed use: yes
Age from 1 year to 3 years 11 months
Ibuprofen s/f susp: 100mg three times a day
Ibuprofen 100mg/5ml oral suspension sugar free
Take one 5ml spoonful three times a day when required for pain relief. Do not exceed the stated dose.
Supply 100 ml.
Age: from 1 year to 3 years 11 months
NHS cost: £1.51
OTC cost: £3.62
Licensed use: yes
Age from 1 year to 5 years 11 months
Paracetamol s/f susp: 120mg to 240mg up to four times a day
Paracetamol 120mg/5ml oral suspension paediatric sugar free
Take one to two 5ml spoonfuls every 4 to 6 hours when required for pain relief. Maximum of 4 doses in 24 hours.
Supply 300 ml.
Age: from 1 year to 5 years 11 months
NHS cost: £1.94
OTC cost: £4.64
Licensed use: yes
Age from 4 years to 6 years 11 months
Ibuprofen s/f susp: 150mg three times a day
Ibuprofen 100mg/5ml oral suspension sugar free
Take 7.5ml three times a day when required for pain relief. Do not exceed the stated dose.
Supply 150 ml.
Age: from 4 years to 6 years 11 months
NHS cost: £2.32
OTC cost: £5.56
Licensed use: yes
Age from 6 years to 11 years 11 months
Paracetamol s/f susp: 250mg to 500mg up to four times a day
Paracetamol 250mg/5ml oral suspension sugar free
Take one to two 5ml spoonfuls every 4 to 6 hours when required for pain relief. Maximum of 4 doses in 24 hours.
Supply 300 ml.
Age: from 6 years to 11 years 11 months
NHS cost: £2.09
OTC cost: £5.00
Licensed use: yes
Age from 7 years to 9 years 11 months
Ibuprofen s/f susp: 200mg up to three times a day
Ibuprofen 100mg/5ml oral suspension sugar free
Take two 5ml spoonfuls three times a day when required for pain relief. Do not exceed the stated dose.
Supply 200 ml.
Age: from 7 years to 9 years 11 months
NHS cost: £3.02
OTC cost: £7.24
Licensed use: yes
Age from 10 years to 11 years 11 months
Ibuprofen s/f susp: 300mg up to three times a day
Ibuprofen 100mg/5ml oral suspension sugar free
Take three 5ml spoonfuls three times a day when required for pain relief. Do not exceed the stated dose.
Supply 300 ml.
Age: from 10 years to 11 years 11 months
NHS cost: £4.64
OTC cost: £11.12
Licensed use: yes
Age from 12 years to 17 years 11 months
Paracetamol tablets: 500mg to 1g up to four times a day
Paracetamol 500mg tablets
Take one or two tablets every 4 to 6 hours when required for pain relief. Maximum of 8 tablets in 24 hours.
Supply 50 tablets.
Age: from 12 years to 17 years 11 months
NHS cost: £0.83
OTC cost: £1.98
Licensed use: yes
Ibuprofen tablets: 200mg to 400mg three to four times a day
Ibuprofen 200mg tablets
Take one or two tablets 3 to 4 times a day when required for pain relief. Do not exceed the stated dose.
Supply 56 tablets.
Age: from 12 years to 17 years 11 months
NHS cost: £1.11
OTC cost: £2.66
Licensed use: yes
Age from 18 years onwards
Paracetamol tablets: 1g up to four times a day
Paracetamol 500mg tablets
Take two tablets every 4 to 6 hours when required for pain relief. Maximum of 8 tablets in 24 hours.
Supply 50 tablets.
Age: from 18 years onwards
NHS cost: £0.83
OTC cost: £1.98
Licensed use: yes
Ibuprofen tablets: 400mg three times a day
Ibuprofen 400mg tablets
Take one tablet three times a day when required for pain relief. Do not exceed the stated dose.
Supply 21 tablets.
Age: from 18 years onwards
NHS cost: £0.46
OTC cost: £1.10
Licensed use: yes

1st-line antibiotic (IF indicated): co-amoxiclav for 7 days

Age from 1 month to 11 months
Co-amoxiclav s/f susp: 0.25ml/kg three times a day
Co-amoxiclav 125mg/31mg/5ml oral suspension sugar free
*WEIGHT REQUIRED* Take 0.25ml per kg bodyweight THREE times a day for 7 days.
Supply 100 ml.
Age: from 1 month to 11 months
NHS cost: £5.05
Licensed use: yes
Co-amoxiclav s/f susp: 0.5ml/kg three times a day
Co-amoxiclav 125mg/31mg/5ml oral suspension sugar free
*WEIGHT REQUIRED* Take 0.5ml per kg bodyweight THREE times a day for 7 days.
Supply 100 ml.
Age: from 1 month to 11 months
NHS cost: £5.05
Licensed use: yes
Age from 1 year to 5 years 11 months
Co-amoxiclav s/f susp: 125/31mg three times a day
Co-amoxiclav 125mg/31mg/5ml oral suspension sugar free
Take one 5ml spoonful three times a day for 7 days.
Supply 100 ml.
Age: from 1 year to 5 years 11 months
NHS cost: £5.05
Licensed use: yes
Co-amoxiclav s/f susp: 250/62mg three times a day
Co-amoxiclav 250mg/62mg/5ml oral suspension sugar free
Take one 5ml spoonful three times a day for 7 days.
Supply 100 ml.
Age: from 1 year to 5 years 11 months
NHS cost: £5.70
Licensed use: yes
Age from 6 years to 11 years 11 months
Co-amoxiclav s/f susp: 250/62mg three times a day (6 years to 11 years 11 months)
Co-amoxiclav 250mg/62mg/5ml oral suspension sugar free
Take one 5ml spoonful three times a day for 7 days.
Supply 100 ml.
Age: from 6 years to 11 years 11 months
NHS cost: £5.70
Licensed use: yes
Co-amoxiclav s/f susp: 500/124mg three times a day
Co-amoxiclav 250mg/62mg/5ml oral suspension sugar free
Take two 5ml spoonfuls three times a day for 7 days.
Supply 200 ml.
Age: from 6 years to 11 years 11 months
NHS cost: £11.40
Licensed use: yes
Age from 12 years onwards
Co-amoxiclav tablets: 250/125mg three times a day
Co-amoxiclav 250mg/125mg tablets
Take one tablet three times a day for 7 days.
Supply 21 tablets.
Age: from 12 years onwards
NHS cost: £5.80
Licensed use: yes
Co-amoxiclav tablets: 500/125mg three times a day
Co-amoxiclav 500mg/125mg tablets
Take one tablet three times a day for 7 days.
Supply 21 tablets.
Age: from 12 years onwards
NHS cost: £11.38
Licensed use: yes

1st-line antibiotic in penicillin allergy (IF indicated)

Age from 1 month to 1 year 11 months
Multi-therapy: Erythromycin 125mg/5ml + metronidazole 200mg/5ml suspension
Erythromycin s/f suspension: 125mg four times a day
Erythromycin ethyl succinate 125mg/5ml oral suspension sugar free
Take one 5ml spoonful four times a day for 7 days.
Supply 200 ml.
Age: from 1 month to 1 year 11 months
NHS cost: £5.46
Licensed use: yes
Metronidazole suspension: 7.5mg/kg three times a day
Metronidazole 200mg/5ml oral suspension
*WEIGHT REQUIRED* Take 7.5mg per kg bodyweight THREE times a day for 7 days. (Max 400mg per dose.)
Supply 100 ml.
Age: from 1 month to 1 year 11 months
NHS cost: £7.70
Licensed use: yes
Age from 3 months to 5 years
Multi-therapy: Clarithromycin + metronidazole: child weighs 8kg to 11.9kg
Clarithromycin suspension: 62.5mg twice a day
Clarithromycin 125mg/5ml oral suspension
Take 2.5ml twice a day for 5 days.
Supply 70 ml.
Age: from 3 months to 5 years
NHS cost: £5.58
Licensed use: yes
Metronidazole suspension: 7.5mg/kg three times a day
Metronidazole 200mg/5ml oral suspension
*WEIGHT REQUIRED* Take 7.5mg per kg bodyweight THREE times a day for 5 days. (Max 400mg per dose.)
Supply 100 ml.
Age: from 3 months to 5 years
NHS cost: £7.70
Licensed use: yes
Age from 6 months to 7 years
Multi-therapy: Clarithromycin + metronidazole: child weighs 12kg to 19.9kg
Clarithromycin suspension: 125mg twice a day
Clarithromycin 125mg/5ml oral suspension
Take one 5ml spoonful twice a day for 5 days.
Supply 70 ml.
Age: from 6 months to 7 years
NHS cost: £5.58
Licensed use: yes
Metronidazole suspension: 7.5mg/kg three times a day
Metronidazole 200mg/5ml oral suspension
*WEIGHT REQUIRED* Take 7.5mg per kg bodyweight THREE times a day for 5 days. (Max 400mg per dose.)
Supply 100 ml.
Age: from 6 months to 7 years
NHS cost: £7.70
Licensed use: yes
Age from 2 years to 11 years 11 months
Multi-therapy: Erythromycin 250mg/5ml + metronidazole 200mg/5ml suspension
Erythromycin s/f suspension: 250mg four times a day
Erythromycin ethyl succinate 250mg/5ml oral suspension sugar free
Take one 5ml spoonful four times a day for 7 days.
Supply 200 ml.
Age: from 2 years to 11 years 11 months
NHS cost: £5.42
Licensed use: yes
Metronidazole suspension: 7.5mg/kg three times a day
Metronidazole 200mg/5ml oral suspension
*WEIGHT REQUIRED* Take 7.5mg per kg bodyweight THREE times a day for 7 days. (Max 400mg per dose.)
Supply 200 ml.
Age: from 2 years to 11 years 11 months
NHS cost: £15.40
Licensed use: yes
Multi-therapy: Erythromycin 500mg/5ml + metronidazole 200mg/5ml suspension
Erythromycin s/f suspension: 500mg four times a day
Erythromycin ethyl succinate 500mg/5ml oral suspension sugar free
Take one 5ml spoonful four times a day for 7 days.
Supply 200 ml.
Age: from 2 years to 11 years 11 months
NHS cost: £11.10
Licensed use: yes
Metronidazole suspension: 7.5mg/kg three times a day
Metronidazole 200mg/5ml oral suspension
*WEIGHT REQUIRED* Take 7.5mg per kg bodyweight THREE times a day for 7 days. (Max 400mg per dose.)
Supply 200 ml.
Age: from 2 years to 11 years 11 months
NHS cost: £15.40
Licensed use: yes
Age from 3 to 10 years
Multi-therapy: Clarithromycin + metronidazole: child weighs 20kg to 20.9kg
Clarithromycin suspension: 187.5mg twice a day
Clarithromycin 125mg/5ml oral suspension
Take 7.5ml twice a day for 5 days.
Supply 100 ml.
Age: from 3 years to 10 years
NHS cost: £9.60
Licensed use: yes
Metronidazole suspension: 7.5mg/kg three times a day
Metronidazole 200mg/5ml oral suspension
*WEIGHT REQUIRED* Take 7.5mg per kg bodyweight THREE times a day for 5 days. (Max 400mg per dose.)
Supply 200 ml.
Age: from 3 years to 10 years
NHS cost: £15.40
Licensed use: yes
Age from 7 years to 11 years 11 months
Multi-therapy: Clarithromycin + metronidazole: child weighs >= 30kg
Clarithromycin suspension: 250mg twice a day
Clarithromycin 250mg/5ml oral suspension
Take one 5ml spoonful twice a day for 5 days.
Supply 70 ml.
Age: from 7 years to 11 years 11 months
NHS cost: £6.72
Licensed use: yes
Metronidazole suspension: 7.5mg/kg three times a day
Metronidazole 200mg/5ml oral suspension
-*WEIGHT REQUIRED* Take 7.5mg per kg bodyweight THREE times a day for 5 days. (Max 400mg per dose.)
Supply 200 ml.
Age: from 7 years to 11 years 11 months
NHS cost: £15.40
Licensed use: yes
Age from 12 years onwards
Multi-therapy: Doxycycline 100mg capsules + metronidazole 400mg tablets
Doxycycline capsules: 100mg twice a day
Doxycycline 100mg capsules
Take one capsule twice a day for 7 days.
Supply 14 capsules.
Age: from 12 years onwards
NHS cost: £4.00
Licensed use: no - off-label dose
Metronidazole tablets: 400mg three times a day
Metronidazole 400mg tablets
Take one tablet three times a day for 7 days.
Supply 21 tablets.
Age: from 12 years onwards
NHS cost: £1.97
Licensed use: yes
Multi-therapy: Erythromycin 250mg e/c + metronidazole 400mg tablets
Metronidazole tablets: 400mg three times a day
Metronidazole 400mg tablets
Take one tablet three times a day for 7 days.
Supply 21 tablets.
Age: from 12 years onwards
NHS cost: £1.97
Licensed use: yes
Erythromycin gastro-resistant tablets: 250mg four times a day
Erythromycin 250mg gastro-resistant tablets
Take one tablet four times a day for 7 days.
Supply 28 tablets.
Age: from 12 years onwards
NHS cost: £1.87
Licensed use: yes
Multi-therapy: Erythromycin 500mg e/c + metronidazole 400mg tablets
Erythromycin gastro-resistant tablets: 500mg four times a day
Erythromycin 250mg gastro-resistant tablets
Take two tablets four times a day for 7 days.
Supply 56 tablets.
Age: from 12 years onwards
NHS cost: £3.54
Licensed use: yes
Metronidazole tablets: 400mg three times a day
Metronidazole 400mg tablets
Take one tablet three times a day for 7 days.
Supply 21 tablets.
Age: from 12 years onwards
NHS cost: £1.97
Licensed use: yes
Multi-therapy: Clarithromycin + metronidazole: from 12 years
Clarithromycin tablets: 250mg twice a day
Clarithromycin 250mg tablets
Take one tablet twice a day for 5 days.
Supply 10 tablets.
Age: from 12 years onwards
NHS cost: £3.90
Licensed use: yes
Metronidazole tablets: 400mg three times a day
Metronidazole 400mg tablets
Take one tablet three times a day for 5 days.
Supply 15 tablets.
Age: from 12 years onwards
NHS cost: £1.41
Licensed use: yes

Tetanus vaccine: primary course

Age from 2 months to 3 years
Primary course: diphtheria+tetanus+pertussis+polio+Hib
Infanrix-IPV + Hib vaccine inj 0.5ml pfs
Give 0.5ml by intramuscular injection. For primary immunization, give three doses at intervals of 1 month between doses.
Supply 1 0.5 ml prefilled syringe.
Age: from 2 months to 3 years
NHS cost: £19.94
Licensed use: yes
Age from 2 months to 9 years 11 months
Primary course: diphtheria+tetanus+pertussis+polio+Hib
Pediacel vaccine suspension for injection 0.5ml vials
Give 0.5ml by intramuscular injection. For primary immunization, give three doses at intervals of 1 month between doses.
Supply 1 0.5ml vial.
Age: from 2 months to 9 years 11 months
NHS cost: £19.94
Licensed use: yes
Age from 10 years onwards
Primary course: low-dose diphtheria+tetanus+polio
Revaxis vaccine suspension for injection 0.5ml pre-filled syringes
Give 0.5ml by deep intramuscular injection. For primary immunization, give three doses at intervals of 1 month between doses.
Supply 1 0.5ml prefilled syringe.
Age: from 10 years onwards
NHS cost: £6.74
Licensed use: yes

Tetanus vaccine: booster dose

Age from 3 years to 9 years 11 months
Booster: low-dose diphtheria+tetanus+pertussis+polio
Repevax vaccine suspension for injection 0.5ml pre-filled syringes
Give 0.5ml by intramuscular injection.
Supply 1 0.5 ml prefilled syringe.
Age: from 3 years to 9 years 11 months
NHS cost: £11.98
Licensed use: yes
Black triangle
Age from 10 years onwards
Booster: low-dose diphtheria+tetanus+polio
Revaxis vaccine suspension for injection 0.5ml pre-filled syringes
Give 0.5ml by intramuscular injection.
Supply 1 0.5 ml prefilled syringe.
Age: from 10 years onwards
NHS cost: £6.74
Licensed use: yes

Scenario: Managing a cat or dog bite

When should I refer someone with an animal bite?

  • Penetrating wounds involving arteries, joints, nerves, muscles, tendons, bones, or the central nervous system. Note: penetrating bites to the hands or feet are at particular risk of infection and serious complications.
  • Facial wounds (excluding very minor wounds) or bites to poorly vascularized areas e.g. ear cartilage/nose cartilage.
  • Devitalized wounds where debridement is required or where there is a possibility of a foreign body (e.g. a tooth) in the wound.
  • Wounds which might benefit from closure, or need reconstructive surgery.
  • Bites where the severity of the injury is difficult to assess.
  • People with severe cellulitis, or with infected bite wounds that are not responding to treatment, or who are systemically unwell.
  • People with an increased risk of infection — including those with diabetes or cirrhosis, those who are immunocompromised, and asplenic individuals (especially if they are not taking prophylactic penicillin).
  • Children with scalp wounds (for X-ray).
  • If an animal has bitten a child, consider the possibility of poor parenting and supervision. Follow local policies for referral of children considered at risk.
  • People who may have been exposed to rabies — seek immediate advice from the Virus Reference Department of the Health Protection Agency.

In depth

How should an animal bite be cared for initially?

  • If possible remove any foreign bodies (e.g. teeth) from the wound.
  • If the wound has just occurred encourage it to bleed, unless it is already bleeding freely.
  • Irrigate thoroughly with warm, running water.
  • Wound closure is rarely advised in primary care. For more information see When to close an animal bite wound.
  • Advise analgesia (ibuprofen or paracetamol) for pain relief, if required.
  • Prescribe prophylactic antibiotics if the wound is less than 48 hours old and the risk of infection is high.
  • Consider if tetanus prophylaxis is required.

In depth

Should I give antibiotic prophylaxis to someone with an animal bite?

  • Prescribe oral antibiotics for:
    • All cat bites, animal bites to the hand, foot, and face; puncture wounds; wounds requiring surgical debridement; wounds involving joints, tendons, ligaments, or suspected fractures.
    • Wounds that have undergone primary closure.
    • People who are at risk of serious wound infection (e.g. those who are diabetic, cirrhotic, asplenic, or immunosuppressed).
    • People with a prosthetic valve or a prosthetic joint.
  • Antibiotics are not generally needed if the wound is more than 2 days old and there is no sign of local or systemic infection.

In depth

Which antibiotic should I use for someone with an animal bite?

  • For prophylaxis and treatment of an infected animal bite prescribe a 7–day course of co-amoxiclav.
  • For people who are allergic to penicillin give metronidazole plus doxycycline, or metronidazole plus oxytetracycline.
  • For children under 12 years old who are allergic to penicillin seek advice from a microbiologist.
  • For animals not covered in this guidance (e.g. pigs) seek specialist advice for the most appropriate antibiotic.

In depth

What follow-up is needed for someone who has had an animal bite?

  • This follow-up advice only applies to people who have not been referred to hospital.
  • If the bite wound is not infected — advise the person to check for signs of infection and if these develop to attend urgently for review.
  • If the wound is infected — review at 24 and 48 hours to ensure the infection is responding to treatment. Advise the person to attend urgently for review if the infection worsens or if they feel increasingly unwell.
  • Follow-up for people who have needed post-exposure prophylaxis for rabies should follow the regimen advised for them by the Virus Reference Department of the Health Protection Agency.

In depth

Prescriptions

Analgesia: use when required

Age from 1 month to 2 months
Paracetamol s/f susp: 30mg to 60mg up to three times a day
Paracetamol 120mg/5ml oral suspension paediatric sugar free
Take 1.25ml to 2.5ml every 8 hours when required for pain relief. Maximum of 3 doses in 24 hours.
Supply 100 ml.
Age: from 1 month to 2 months
NHS cost: £0.44
OTC cost: £0.78
Licensed use: no - off-label age
Ibuprofen s/f susp: 5mg/kg three to four times a day (> 5kg)
Ibuprofen 100mg/5ml oral suspension sugar free
*WEIGHT REQUIRED* Take 5mg per kg bodyweight three to four times a day when required for relief of pain. Do not exceed the stated dose.
Supply 50 ml.
Age: from 1 month to 2 months
NHS cost: £0.76
OTC cost: £1.82
Licensed use: no - off-label indication
Age from 3 to 5 months
Ibuprofen s/f susp: 50mg three times a day
Ibuprofen 100mg/5ml oral suspension sugar free
Take 2.5ml three times a day when required for pain relief. Do not exceed the stated dose.
Supply 50 ml.
Age: from 3 months to 5 months
NHS cost: £0.76
OTC cost: £1.82
Licensed use: yes
Age from 3 to 11 months
Paracetamol s/f susp: 60mg to 120mg up to four times a day
Paracetamol 120mg/5ml oral suspension paediatric sugar free
Take 2.5ml to 5ml every 4 to 6 hours when required for pain relief. Maximum of 4 doses in 24 hours.
Supply 150 ml.
Age: from 3 months to 11 months
NHS cost: £0.97
OTC cost: £2.32
Licensed use: yes
Age from 6 to 11 months
Ibuprofen s/f susp: 50mg three to four times a day
Ibuprofen 100mg/5ml oral suspension sugar free
Take 2.5ml three to four times a day when required for pain relief. Do not exceed the stated dose.
Supply 100 ml.
Age: from 6 months to 11 months
NHS cost: £1.51
OTC cost: £3.62
Licensed use: yes
Age from 1 year to 3 years 11 months
Ibuprofen s/f susp: 100mg three times a day
Ibuprofen 100mg/5ml oral suspension sugar free
Take one 5ml spoonful three times a day when required for pain relief. Do not exceed the stated dose.
Supply 100 ml.
Age: from 1 year to 3 years 11 months
NHS cost: £1.51
OTC cost: £3.62
Licensed use: yes
Age from 1 year to 5 years 11 months
Paracetamol s/f susp: 120mg to 240mg up to four times a day
Paracetamol 120mg/5ml oral suspension paediatric sugar free
Take one to two 5ml spoonfuls every 4 to 6 hours when required for pain relief. Maximum of 4 doses in 24 hours.
Supply 300 ml.
Age: from 1 year to 5 years 11 months
NHS cost: £1.94
OTC cost: £4.64
Licensed use: yes
Age from 4 years to 6 years 11 months
Ibuprofen s/f susp: 150mg three times a day
Ibuprofen 100mg/5ml oral suspension sugar free
Take 7.5ml three times a day when required for pain relief. Do not exceed the stated dose.
Supply 150 ml.
Age: from 4 years to 6 years 11 months
NHS cost: £2.32
OTC cost: £5.56
Licensed use: yes
Age from 6 years to 11 years 11 months
Paracetamol s/f susp: 250mg to 500mg up to four times a day
Paracetamol 250mg/5ml oral suspension sugar free
Take one to two 5ml spoonfuls every 4 to 6 hours when required for pain relief. Maximum of 4 doses in 24 hours.
Supply 300 ml.
Age: from 6 years to 11 years 11 months
NHS cost: £2.09
OTC cost: £5.00
Licensed use: yes
Age from 7 years to 9 years 11 months
Ibuprofen s/f susp: 200mg up to three times a day
Ibuprofen 100mg/5ml oral suspension sugar free
Take two 5ml spoonfuls three times a day when required for pain relief. Do not exceed the stated dose.
Supply 200 ml.
Age: from 7 years to 9 years 11 months
NHS cost: £3.02
OTC cost: £7.24
Licensed use: yes
Age from 10 years to 11 years 11 months
Ibuprofen s/f susp: 300mg up to three times a day
Ibuprofen 100mg/5ml oral suspension sugar free
Take three 5ml spoonfuls three times a day when required for pain relief. Do not exceed the stated dose.
Supply 300 ml.
Age: from 10 years to 11 years 11 months
NHS cost: £4.64
OTC cost: £11.12
Licensed use: yes
Age from 12 years to 17 years 11 months
Paracetamol tablets: 500mg to 1g up to four times a day
Paracetamol 500mg tablets
Take one or two tablets every 4 to 6 hours when required for pain relief. Maximum of 8 tablets in 24 hours.
Supply 50 tablets.
Age: from 12 years to 17 years 11 months
NHS cost: £0.83
OTC cost: £1.98
Licensed use: yes
Ibuprofen tablets: 200mg to 400mg three to four times a day
Ibuprofen 200mg tablets
Take one or two tablets 3 to 4 times a day when required for pain relief. Do not exceed the stated dose.
Supply 56 tablets.
Age: from 12 years to 17 years 11 months
NHS cost: £1.11
OTC cost: £2.66
Licensed use: yes
Age from 18 years onwards
Paracetamol tablets: 1g up to four times a day
Paracetamol 500mg tablets
Take two tablets every 4 to 6 hours when required for pain relief. Maximum of 8 tablets in 24 hours.
Supply 50 tablets.
Age: from 18 years onwards
NHS cost: £0.83
OTC cost: £1.98
Licensed use: yes
Ibuprofen tablets: 400mg three times a day
Ibuprofen 400mg tablets
Take one tablet three times a day when required for pain relief. Do not exceed the stated dose.
Supply 21 tablets.
Age: from 18 years onwards
NHS cost: £0.46
OTC cost: £1.10
Licensed use: yes

1st-line antibiotic (IF indicated): co-amoxiclav for 7 days

Age from 1 month to 11 months
Co-amoxiclav s/f susp: 0.25ml/kg three times a day
Co-amoxiclav 125mg/31mg/5ml oral suspension sugar free
*WEIGHT REQUIRED* Take 0.25ml per kg bodyweight THREE times a day for 7 days.
Supply 100 ml.
Age: from 1 month to 11 months
NHS cost: £5.05
Licensed use: yes
Co-amoxiclav s/f susp: 0.5ml/kg three times a day
Co-amoxiclav 125mg/31mg/5ml oral suspension sugar free
*WEIGHT REQUIRED* Take 0.5ml per kg bodyweight THREE times a day for 7 days.
Supply 100 ml.
Age: from 1 month to 11 months
NHS cost: £5.05
Licensed use: yes
Age from 1 year to 5 years 11 months
Co-amoxiclav s/f susp: 125/31mg three times a day
Co-amoxiclav 125mg/31mg/5ml oral suspension sugar free
Take one 5ml spoonful three times a day for 7 days.
Supply 100 ml.
Age: from 1 year to 5 years 11 months
NHS cost: £5.05
Licensed use: yes
Co-amoxiclav s/f susp: 250/62mg three times a day
Co-amoxiclav 250mg/62mg/5ml oral suspension sugar free
Take one 5ml spoonful three times a day for 7 days.
Supply 100 ml.
Age: from 1 year to 5 years 11 months
NHS cost: £5.70
Licensed use: yes
Age from 6 years to 11 years 11 months
Co-amoxiclav s/f susp: 250/62mg three times a day (6 years to 11 years 11 months)
Co-amoxiclav 250mg/62mg/5ml oral suspension sugar free
Take one 5ml spoonful three times a day for 7 days.
Supply 100 ml.
Age: from 6 years to 11 years 11 months
NHS cost: £5.70
Licensed use: yes
Co-amoxiclav s/f susp: 500/124mg three times a day
Co-amoxiclav 250mg/62mg/5ml oral suspension sugar free
Take two 5ml spoonfuls three times a day for 7 days.
Supply 200 ml.
Age: from 6 years to 11 years 11 months
NHS cost: £11.40
Licensed use: yes
Age from 12 years onwards
Co-amoxiclav tablets: 250/125mg three times a day
Co-amoxiclav 250mg/125mg tablets
Take one tablet three times a day for 7 days.
Supply 21 tablets.
Age: from 12 years onwards
NHS cost: £5.80
Licensed use: yes
Co-amoxiclav tablets: 500/125mg three times a day
Co-amoxiclav 500mg/125mg tablets
Take one tablet three times a day for 7 days.
Supply 21 tablets.
Age: from 12 years onwards
NHS cost: £11.38
Licensed use: yes

1st-line antibiotic in penicillin allergy (IF indicated)

Age from 12 years onwards
Multi-therapy: Doxycycline 100mg capsules + metronidazole 400mg tablets
Doxycycline capsules: 100mg twice a day
Doxycycline 100mg capsules
Take one capsule twice a day for 7 days.
Supply 14 capsules.
Age: from 12 years onwards
NHS cost: £4.00
Licensed use: no - off-label dose
Metronidazole tablets: 400mg three times a day
Metronidazole 400mg tablets
Take one tablet three times a day for 7 days.
Supply 21 tablets.
Age: from 12 years onwards
NHS cost: £1.97
Licensed use: yes
Multi-therapy: Oxytetracycline 250mg + metronidazole 400mg tablets
Metronidazole tablets: 400mg three times a day
Metronidazole 400mg tablets
Take one tablet three times a day for 7 days.
Supply 21 tablets.
Age: from 12 years onwards
NHS cost: £1.97
Licensed use: yes
Oxytetracycline tablets: 250mg four times a day
Oxytetracycline 250mg tablets
Take one tablet four times a day for 7 days.
Supply 28 tablets.
Age: from 12 years onwards
NHS cost: £1.62
Licensed use: yes
Multi-therapy: Oxytetracycline 500mg + metronidazole 400mg tablets
Metronidazole tablets: 400mg three times a day
Metronidazole 400mg tablets
Take one tablet three times a day for 7 days.
Supply 21 tablets.
Age: from 12 years onwards
NHS cost: £1.97
Licensed use: yes
Oxytetracycline tablets: 500mg four times a day
Oxytetracycline 250mg tablets
Take two tablets four times a day for 7 days.
Supply 56 tablets.
Age: from 12 years onwards
NHS cost: £3.94
Licensed use: yes

Tetanus vaccine: primary course

Age from 2 months to 3 years
Primary course: diphtheria+tetanus+pertussis+polio+Hib
Infanrix-IPV + Hib vaccine inj 0.5ml pfs
Give 0.5ml by intramuscular injection. For primary immunization, give three doses at intervals of 1 month between doses.
Supply 1 0.5 ml prefilled syringe.
Age: from 2 months to 3 years
NHS cost: £19.94
Licensed use: yes
Age from 2 months to 9 years 11 months
Primary course: diphtheria+tetanus+pertussis+polio+Hib
Pediacel vaccine suspension for injection 0.5ml vials
Give 0.5ml by intramuscular injection. For primary immunization, give three doses at intervals of 1 month between doses.
Supply 1 0.5ml vial.
Age: from 2 months to 9 years 11 months
NHS cost: £19.94
Licensed use: yes
Age from 10 years onwards
Primary course: low-dose diphtheria+tetanus+polio
Revaxis vaccine suspension for injection 0.5ml pre-filled syringes
Give 0.5ml by deep intramuscular injection. For primary immunization, give three doses at intervals of 1 month between doses.
Supply 1 0.5ml prefilled syringe.
Age: from 10 years onwards
NHS cost: £6.74
Licensed use: yes

Tetanus vaccine: booster dose

Age from 3 years to 9 years 11 months
Booster: low-dose diphtheria+tetanus+pertussis+polio
Repevax vaccine suspension for injection 0.5ml pre-filled syringes
Give 0.5ml by intramuscular injection.
Supply 1 0.5 ml prefilled syringe.
Age: from 3 years to 9 years 11 months
NHS cost: £11.98
Licensed use: yes
Black triangle
Age from 10 years onwards
Booster: low-dose diphtheria+tetanus+polio
Revaxis vaccine suspension for injection 0.5ml pre-filled syringes
Give 0.5ml by intramuscular injection.
Supply 1 0.5 ml prefilled syringe.
Age: from 10 years onwards
NHS cost: £6.74
Licensed use: yes

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