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Breast pain - cyclical - Management
What is the second-line treatment for cyclical breast pain?

  • If the pain is severe enough to affect quality of life and does not respond to first-line treatment:
    • Ask the woman to keep a pain chart for a minimum of 2 months (if she has not already done so) to evaluate the severity and timing of the pain, and its response to treatment.
    • Consider referring to a specialist for other treatment options including:
      • Danazol (an anti-gonadotrophin).
      • Tamoxifen (an oestrogen-receptor antagonist).
      • Goserelin injections (a gonadorelin analogue inhibiting gonadotrophin release), used in conjunction with hormone replacement therapy to relieve adverse effects.
      • Gestrinone (inhibits pituitary gonadotrophin).
      • Toremifene (a selective oestrogen-receptor modulator).

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