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Candida - oral - Prescribing information
Children
- Miconazole oral gel (20 mg/mL) is rarely contraindicated in children.
- Advise the child (or carer) to:
- Apply the gel directly to the affected area with a clean finger, and to leave it in contact with the mucosa for as long as possible.
- Miconazole gel is not licensed in children under 4 months of age because of the risks of choking if it is not applied carefully. Care should be taken to ensure that the gel does not obstruct the throat in infants (avoid application to the back of the throat and subdivide doses if necessary).
- The oral gel should be applied:
- Two to four times a day in neonates, after feeds.
- Twice a day in infants and children under 6 years of age, after feeds or food.
- Four times a day in children older than 6 years of age, after food.
Basis for recommendations
- These recommendations are based on a narrative review [Samaranayake et al, 2009], the product licence for Daktarin® in children older than 4 months of age [ABPI Medicines Compendium, 2008a], and the British National Formulary for Children [BNF for Children, 2008].
- There are unlikely to be contraindications to miconazole in this age group, such as concomitant use of drugs metabolized by cytochrome P450 enzymes (for example warfarin and statins).
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