Print Print
CKS is no longer commissioned by the National Institute for Health and Clinical Excellence (NICE). NICE remains committed to providing a replacement service for CKS and is currently reviewing its options. In the meantime, although CKS content is now not being maintained, it still remains relevant and will continue to be made available. CKS content was generated under a programme of topic creation and update. To check if the topic you are viewing is current or out of date, please refer to the topic publication details by clicking on the 'How up-to-date is this topic?' link in the left hand menu on individual topic pages.

Chickenpox - Background information
What is it?

  • Chickenpox is an acute disease caused by varicella-zoster virus. It is characterized by a vesicular rash, and often fever and malaise [Heininger and Seward, 2006].
  • Varicella is very infectious; up to 90% of susceptible contacts develop the disease [HPA, 2006].
  • Transmission is by personal contact or droplet spread, with an incubation period (the time from becoming infected until symptoms appear) of 1–3 weeks [DH, 2006; HPA, 2006].
  • Chickenpox is infectious from 1–2 days before the rash appears until the vesicles are dry or have crusted over, usually 5–6 days after the onset of the illness (this period may be longer in people who are immunosuppressed) [DH, 2006; HPA, 2006].
  • Once the infection has subsided, the virus persists in sensory nerve ganglia of the dorsal root. Years or decades later, it can reactivate and cause herpes zoster (shingles). See the CKS topics on Post-herpetic neuralgia and Shingles.
  • It is possible to develop chickenpox after exposure to a person with shingles, but it is not possible to develop shingles from exposure to a person with chickenpox [HPA, 2006].

© NHS Institute for Innovation and Improvement