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Chronic obstructive pulmonary disease - Management
Second-line antibiotic

Age from 16 years onwards
Doxycycline 100mg once a day - IF not already tried
Doxycycline 100mg capsules
Take TWO capsules now and then take ONE capsule once a day for the next 6 days.
Supply 8 capsules.
Age: from 16 years onwards
NHS cost: £1.16
Licensed use: yes
Patient information: Take doxycycline capsules during a meal. Swallow capsules whole with plenty of fluid while sitting or standing. Do not sunbathe or use sunlamps while taking this medicine.
Erythromycin tabs: 500mg 4x/day - IF not already tried
Erythromycin 250mg gastro-resistant tablets
Take two tablets four times a day for 7 days.
Supply 56 tablets.
Age: from 16 years onwards
NHS cost: £3.08
Licensed use: yes
Clarithromycin tabs: 500mg twice/day - IF not already tried
Clarithromycin 500mg tablets
Take one tablet twice a day for 7 days.
Supply 14 tablets.
Age: from 16 years onwards
NHS cost: £4.10
Licensed use: yes
Co-amoxiclav 500/125mg three times a day
Co-amoxiclav 500mg/125mg tablets
Take one tablet three times a day for 7 days.
Supply 21 tablets.
Age: from 16 years onwards
NHS cost: £4.38
Licensed use: yes

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