Print Print
CKS is no longer commissioned by the National Institute for Health and Clinical Excellence (NICE). NICE remains committed to providing a replacement service for CKS and is currently reviewing its options. In the meantime, although CKS content is now not being maintained, it still remains relevant and will continue to be made available. CKS content was generated under a programme of topic creation and update. To check if the topic you are viewing is current or out of date, please refer to the topic publication details by clicking on the 'How up-to-date is this topic?' link in the left hand menu on individual topic pages.

Contraception - Management
How does epilepsy influence choice?

  • Women with a history of epilepsy who are not taking anticonvulsants
    • All methods can be used without restriction.
  • Women taking anticonvulsants that do not induce liver enzymes (i.e. gabapentin, levetiracetam, valproate, and vigabatrin)
    • All methods can be used without restriction, except that sterilization should be undertaken with caution and seizures should be adequately controlled.
  • Women taking anticonvulsants that induce liver enzymes (phenytoin, carbamazepine, barbiturates, primidone, topiramate, oxcarbazepine)
    • Methods that can be used without restriction: depot medroxyprogesterone acetate, copper intrauterine devices, the levonorgestrel-releasing intrauterine system, barrier methods, and natural family planning methods.
    • Methods that can generally be used (benefits generally outweigh the risks): progestogen-only implant, depot norethisterone enantate.
    • Sterilization can be done with caution.
    • Methods that should not usually be used (risks usually outweigh the benefits): combined oral contraceptive, combined contraceptive patch, combined contraceptive vaginal ring, and progestogen-only pill.
      • If combined oral contraceptives are chosen, dose adjustment may be needed. For more information about dose adjustment, see Liver enzyme-inducing drugs.
  • Women taking lamotrigine
    • Methods that can be used without restriction: progestogen-only pills, injectables and implants, copper intrauterine devices, the levonorgestrel-releasing intrauterine system, barrier methods, and natural family planning methods.
    • Methods that should not usually be used (risks usually outweigh the benefits): combined oral contraceptives, combined contraceptive patch, combined contraceptive vaginal ring.
      • If combined oral contraception is chosen, dose adjustment may be needed. For more information about dose adjustment, see Lamotrigine and Drug interactions.

In depth

© NHS Institute for Innovation and Improvement