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Corneal superficial injury - Management
Which topical antibiotic should I use in pregnancy or breastfeeding?
- Topical fusidic acid may be used during pregnancy or when breastfeeding.
- Topical chloramphenicol may also be used during breastfeeding. However it is not recommended during pregnancy [UKMiCentral, 2004; Schaefer et al, 2007].
Basis for recommendation
- Fusidic acid is not known to be harmful when used during pregnancy or breastfeeding [BNF 54, 2007].
- There is no evidence that chloramphenicol is associated with congenital abnormalities. However maternal treatment with chloramphenicol in the last few weeks of pregnancy may cause grey baby syndrome (feeding problems, vomiting, ash-grey skin, respiratory distress, and cardiovascular collapse [Micromedex, 2007]).
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