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Corneal superficial injury - Management
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How do I assess a superficial corneal injury?
- Determine how the injury was caused, in particular if it was due to chemicals or a high-velocity foreign body. It is important not to miss a penetrating eye injury.
- Assess for the degree of injury:
- Test visual acuity in both eyes with a Snellen chart, and document carefully.
- Test the extra-ocular eye muscles by assessing eye movements in all directions and eyelid function.
- Examine both pupils for size and reaction to light.
- Look for the presence of a subconjunctival haemorrhage.
- Look for the presence of a hyphaema (blood in the anterior chamber).
- Use fluorescein stain to assess the size, shape, and position of the corneal abrasion, and document carefully.
- Use a slit lamp (if available) to reveal corneal oedema, epithelial disruption, or anterior chamber penetration.
- Consider using a topical anaesthetic (e.g. proxymetacaine, or tetracaine) if examination is difficult. Topical anaesthetics are also available combined with fluorescein.
In depth
When should I refer to an ophthalmologist?
- Refer immediately to the emergency eye service:
- All high-velocity injuries.
- All chemical injuries.
- If there is a foreign body that cannot be removed.
- If any of the following clinical features are present:
- Pain which is not relieved by topical local anaesthetic.
- A reduction in visual acuity.
- Large abrasions.
- Corneal opacities.
- Rust rings that remain after removal of a metallic foreign body.
- Hyphaema.
- A distorted pupil.
- Suspected damage to the retina.
- Deep laceration of the orbit.
- Subconjunctival haemorrhage, if it tracks posteriorly and there is a history consistent with a possible orbital fracture.
- Marginal lacerations.
- Also urgently refer people with:
- Persistent symptoms after 72 hours.
- Worsening symptoms.
- A corneal abrasion which shows no improvement (healing) on a daily basis.
- Recurrent abrasions may be referred non-urgently.
In depth
How should I manage a superficial corneal injury that is not referred?
- Remove the foreign body if present (and this is appropriate).
- Offer or advise analgesia for pain relief.
- Paracetamol or ibuprofen is recommended first-line.
- Consider offering a one off dose of a cycloplegic (e.g. cyclopentolate 0.5%) if available.
- To prevent secondary infection prescribe:
- Topical chloramphenicol first-line, four times a day, for 7 days.
- Consider prescribing fusidic acid, twice a day (7 days), as an alternative if:
- Treatment four times a day is impractical (e.g. in children or elderly people).
- The person is pregnant.
- There is a personal or family history of blood dyscrasias, such as aplastic anaemia.
- The person is intolerant of chloramphenicol.
- Advise the person not to wear contact lenses until the corneal abrasion has completely healed and, where possible, for 24 hours after finishing treatment with topical antibiotics.
In depth
What follow up is required?
- Re-examine the eye, using fluorescein stain, after 24 hours:
- If the corneal abrasion is reducing in size, re-examine daily to confirm the abrasion is healing. If it has not healed after 72 hours, refer urgently to specialist eye services in secondary care.
- If the corneal abrasion is not reducing in size, refer urgently to secondary care.
- Any worsening symptoms such as increased pain or reduced visual acuity should prompt a thorough re-examination for a foreign body, and an urgent referral to specialist eye services in secondary care.
In depth
Prescriptions
Chloramphenicol eye preparations
Age from 1 month onwards
Chloramphenicol 0.5% eye drops
Chloramphenicol 0.5% eye drops
Put one drop into the affected eye(s) four times a day for 7 days
Supply 10 ml.
Chloramphenicol 1% eye ointment
Chloramphenicol 1% eye ointment
Put a small amount into the affected eye(s) three or four times a day
Supply 4 grams.
Multi-therapy: Chloramphenicol 0.5% eye drops + 1% eye ointment
Chloramphenicol 1% eye ointment
Chloramphenicol 1% eye ointment
Put a small amount into the affected eye(s) at bedtime for 7 days.
Supply 4 grams.
Chloramphenicol 0.5% eye drops
Chloramphenicol 0.5% eye drops
Put one drop into the affected eye(s) four times a day for 7 days
Supply 10 ml.
Fusidic acid eye drops
Age from 1 month onwards
Fusidic acid 1% eye drops
Fusidic acid 1% modified-release eye drops
Put one drop into the affected eye(s) twice a day for 7 days.
Supply 5 grams.
Analgesia: use when required
Age from 1 month to 2 months
Paracetamol s/f susp: 30mg to 60mg up to three times a day
Paracetamol 120mg/5ml oral suspension paediatric sugar free
Take 1.25ml to 2.5ml every 8 hours when required for pain relief. Maximum of 3 doses in 24 hours.
Supply 100 ml.
Ibuprofen s/f susp: 5mg/kg three to four times a day (> 5kg)
Ibuprofen 100mg/5ml oral suspension sugar free
*WEIGHT REQUIRED* Take 5mg per kg bodyweight three to four times a day when required for relief of pain. Do not exceed the stated dose.
Supply 50 ml.
Age from 3 to 5 months
Ibuprofen s/f susp: 50mg three times a day
Ibuprofen 100mg/5ml oral suspension sugar free
Take 2.5ml three times a day when required for pain relief. Do not exceed the stated dose.
Supply 50 ml.
Age from 3 to 11 months
Paracetamol s/f susp: 60mg to 120mg up to four times a day
Paracetamol 120mg/5ml oral suspension paediatric sugar free
Take 2.5ml to 5ml every 4 to 6 hours when required for pain relief. Maximum of 4 doses in 24 hours.
Supply 150 ml.
Age from 6 to 11 months
Ibuprofen s/f susp: 50mg three to four times a day
Ibuprofen 100mg/5ml oral suspension sugar free
Take 2.5ml three to four times a day when required for pain relief. Do not exceed the stated dose.
Supply 100 ml.
Age from 1 year to 3 years 11 months
Ibuprofen s/f susp: 100mg three times a day
Ibuprofen 100mg/5ml oral suspension sugar free
Take one 5ml spoonful three times a day when required for pain relief. Do not exceed the stated dose.
Supply 100 ml.
Age from 1 year to 5 years 11 months
Paracetamol s/f susp: 120mg to 240mg up to four times a day
Paracetamol 120mg/5ml oral suspension paediatric sugar free
Take one to two 5ml spoonfuls every 4 to 6 hours when required for pain relief. Maximum of 4 doses in 24 hours.
Supply 300 ml.
Age from 4 years to 6 years 11 months
Ibuprofen s/f susp: 150mg three times a day
Ibuprofen 100mg/5ml oral suspension sugar free
Take 7.5ml three times a day when required for pain relief. Do not exceed the stated dose.
Supply 150 ml.
Age from 6 years to 11 years 11 months
Paracetamol s/f susp: 250mg to 500mg up to four times a day
Paracetamol 250mg/5ml oral suspension sugar free
Take one to two 5ml spoonfuls every 4 to 6 hours when required for pain relief. Maximum of 4 doses in 24 hours.
Supply 300 ml.
Age from 7 years to 9 years 11 months
Ibuprofen s/f susp: 200mg up to three times a day
Ibuprofen 100mg/5ml oral suspension sugar free
Take two 5ml spoonfuls three times a day when required for pain relief. Do not exceed the stated dose.
Supply 200 ml.
Age from 10 years to 11 years 11 months
Ibuprofen s/f susp: 300mg up to three times a day
Ibuprofen 100mg/5ml oral suspension sugar free
Take three 5ml spoonfuls three times a day when required for pain relief. Do not exceed the stated dose.
Supply 300 ml.
Age from 12 years to 17 years 11 months
Paracetamol tablets: 500mg to 1g up to four times a day
Paracetamol 500mg tablets
Take one or two tablets every 4 to 6 hours when required for pain relief. Maximum of 8 tablets in 24 hours.
Supply 50 tablets.
Ibuprofen tablets: 200mg to 400mg three to four times a day
Ibuprofen 200mg tablets
Take one or two tablets 3 to 4 times a day when required for pain relief. Do not exceed the stated dose.
Supply 56 tablets.
Age from 18 years onwards
Paracetamol tablets: 1g up to four times a day
Paracetamol 500mg tablets
Take two tablets every 4 to 6 hours when required for pain relief. Maximum of 8 tablets in 24 hours.
Supply 50 tablets.
Ibuprofen tablets: 400mg three times a day
Ibuprofen 400mg tablets
Take one tablet three times a day when required for pain relief. Do not exceed the stated dose.
Supply 21 tablets.
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