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Cough - acute with chest signs in children - Management
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Introduction

  • Community-acquired pneumonia is an acute infection of the lung parenchyma, acquired in the community, that may be caused by bacteria, atypical bacteria, or viral infections.

How do I assess a child with a respiratory tract infection and chest signs on examination?

  • A child is considered to be at high risk if any of the following features are present:
    • Respiratory rate (RR) > 60/minute, apnoea or grunting, moderate or severe chest indrawing
    • Oxygen saturations < 90% on air
    • No response to social cues, they are unable to be roused, or if rousable they do not stay awake
    • Appears ill to healthcare professional
    • Reduced skin turgor
    • Age < 3 months and temperature > 38°C, or age 3–6 months and temperature > 39°C
  • A child is considered to be at intermediate risk if they have no high risk features and have any of the following features:
    • Age < 12 months and RR > 50/minute, or age > 12 months and RR > 40/minute, nasal flaring, crackles (pneumonia or bronchiolitis)
    • Oxygen saturation < 95% on air
    • Pallor reported by parent/carer
    • No response to normal social cues, awakes only with prolonged stimulation, decreased activity
    • Poor feeding in infants (less than 50% of normal fluid intake in preceding 24 hours), dry mucous membrane, reduced urine output
    • Capillary refill time > 3 seconds
    • Fever > 5 days duration
  • A child is considered to be at low risk if no features of intermediate or high risk are present.
  • Note: risk is higher in young infants, infants with syndromes or who were premature, and in children with any significant medical history, such as chronic lung disease or congenital heart disease. These additional factors should be considered before deciding on the level of risk.
  • Assess the ability of the child's carers to cope with the ill child.

In depth

How do I manage a child with community-acquired pneumonia?

  • Children with community-acquired pneumonia and any high risk features — admit immediately.
  • Children with community-acquired pneumonia at intermediate risk — consider hospital assessment. The threshold for arranging this should be low. Arrange if the child has any significant health problems such as chronic respiratory disease or congenital heart disease, or the carers are not able to cope.
  • Prescribe an antibiotic for children managed at home:
    • For children less than 5 years of age — amoxicillin is the first-choice. For a child allergic to penicillin, a macrolide (erythromycin or clarithromycin) is an alternative.
    • For a child over 5 years of age — prescribe either amoxicillin or a macrolide. Prescribe a macrolide for children allergic to penicillin and at times when there is a known Mycoplasma outbreak.
  • For children who are managed at home advise carers to check on the child regularly, including through the night, and seek medical advice if they are unable to cope or if the child deteriorates, particularly if:
    • The breathing rate increases, or if there are any episodes of apnoea or signs of increased effort of breathing.
    • A baby takes less than 50% of its normal feeds, or there are signs of dehydration such as dry mouth or infrequent passage of urine.
    • The child becomes less responsive or difficult to rouse.
    • A persistent increase in fever develops.
  • If a child deteriorates on treatment or does not improve after 48 hours of treatment, review and refer for hospital assessment.

In depth

What self-care advice should I give to a carer of a child with viral-induced wheeze, bronchiolitis, or pneumonia?

  • Treat a child who is feeling miserable due to fever with either paracetamol or ibuprofen. Do not try to reduce fever by under-dressing the child or by tepid sponging.
    • If there is a lack of effect with one treatment alone then consider alternate use of ibuprofen and paracetamol every 4 hours.
  • Encourage the child to take fluids regularly. Continue breastfeeding as normal.

In depth

Table: Risk assessment of a child with a respiratory tract infection

Table 1. Assessment of risk in a child with a cough and signs in the chest on examination.
 
Intermediate risk
High risk
Respiratory rate (RR)
Age < 12 months and RR > 50/minute
Age > 12 months and RR > 40/minute
RR > 60/minute
Other respiratory features
Nasal flaring
Crackles (pneumonia or bronchiolitis)
Oxygen saturation < 95% on air*
Apnoea or grunting
Moderate or severe chest indrawing
Oxygen saturations < 90% on air*
Colour
Pallor reported by parent/carer
Pale/mottled/ashen/blue
Activity
No response to normal social cues
Awakes only with prolonged stimulation
Decreased activity
No response to social cues
Unable to be roused, or if rousable does not stay awake
Appears ill to healthcare professional
Hydration/feeding
Poor feeding in infants (less than 50% of normal fluid intake in preceding 24 hours)
Dry mucous membrane
Reduced urine output
Capillary refill time > 3 seconds
Reduced skin turgor
Temperature
Fever > 5 days duration
Age < 3 months and temperature > 38°C
Age 3–6 months and temperature > 39°C
* May not be available in primary care.
† Activity and appearance are highly subjective and are considered poor markers of severity by some experts.
  • A child is considered to be at low risk if no features of intermediate or high risk are present.
  • Note: risk is higher in young infants, infants with syndromes or who were premature, and in children with any significant medical history, such as chronic lung disease or congenital heart disease. These additional factors should be considered before deciding on the level of risk.
  • Assess the ability of the child's carers to cope with the ill child.

Prescriptions

Analgesia/antipyretic: use when required

Age from 1 month to 2 months
Paracetamol s/f susp: 30 to 60mg up to three times a day
Paracetamol 120mg/5ml oral suspension paediatric sugar free
Take 1.25ml to 2.5ml every 8 hours when required for relief of pain or high temperature. Maximum of three doses in 24 hours.
Supply 100 ml.
Age: from 1 month to 2 months
NHS cost: £0.43
OTC cost: £0.76
Licensed use: no - off-label age
Ibuprofen s/f susp: 5mg/kg three to four times a day (> 5kg)
Ibuprofen 100mg/5ml oral suspension sugar free
*WEIGHT REQUIRED* Take 5mg per kg bodyweight three to four times a day when required to relieve pain or high temperature. Do not exceed the stated dose.
Supply 50 ml.
Age: from 1 month to 2 months
NHS cost: £0.82
Licensed use: no - off-label age
Age from 3 to 5 months
Ibuprofen s/f susp: 50mg three times a day
Ibuprofen 100mg/5ml oral suspension sugar free
Take 2.5ml three times a day when required for relief of pain or high temperature. Do not exceed the stated dose.
Supply 50 ml.
Age: from 3 months to 5 months
NHS cost: £0.82
OTC cost: £1.45
Licensed use: yes
Age from 3 to 11 months
Paracetamol s/f susp: 60 to 120mg up to four times a day
Paracetamol 120mg/5ml oral suspension paediatric sugar free
Take 2.5ml to 5ml every 4 to 6 hours when required for relief of pain or high temperature. Maximum of 4 doses in 24 hours.
Supply 150 ml.
Age: from 3 months to 11 months
NHS cost: £0.84
OTC cost: £1.48
Licensed use: yes
Age from 6 to 11 months
Ibuprofen s/f susp: 50mg three to four times a day
Ibuprofen 100mg/5ml oral suspension sugar free
Take 2.5ml three to four times a day when required for relief of pain or high temperature. Do not exceed the stated dose.
Supply 100 ml.
Age: from 6 months to 11 months
NHS cost: £1.64
OTC cost: £2.89
Licensed use: yes
Age from 1 year to 3 years 11 months
Ibuprofen s/f susp: 100mg three times a day
Ibuprofen 100mg/5ml oral suspension sugar free
Take one 5ml spoonful three times a day when required for relief of pain or high temperature. Do not exceed the stated dose.
Supply 100 ml.
Age: from 1 year to 3 years 11 months
NHS cost: £1.64
OTC cost: £2.89
Licensed use: yes
Age from 1 year to 5 years 11 months
Paracetamol s/f susp: 120mg to 240mg up to four times a day
Paracetamol 120mg/5ml oral suspension paediatric sugar free
Take one to two 5ml spoonfuls every 4 to 6 hours when required for relief of pain or high temperature. Maximum of 4 doses in 24 hours.
Supply 300 ml.
Age: from 1 year to 5 years 11 months
NHS cost: £1.68
OTC cost: £2.97
Licensed use: yes
Age from 4 years to 6 years 11 months
Ibuprofen s/f susp: 150mg three times a day
Ibuprofen 100mg/5ml oral suspension sugar free
Take 7.5ml three times a day when required for the relief of pain or high temperature. Do not exceed the stated dose.
Supply 150 ml.
Age: from 4 years to 6 years 11 months
NHS cost: £2.32
OTC cost: £4.10
Licensed use: yes
Age from 6 years to 11 years 11 months
Paracetamol s/f susp: 250mg to 500mg up to four times a day
Paracetamol 250mg/5ml oral suspension sugar free
Take one to two 5ml spoonfuls every 4 to 6 hours when required for relief of pain or high temperature. Maximum of 4 doses in 24 hours.
Supply 300 ml.
Age: from 6 years to 11 years 11 months
NHS cost: £2.23
OTC cost: £3.94
Licensed use: yes
Age from 7 years to 9 years 11 months
Ibuprofen s/f susp: 200mg three times a day
Ibuprofen 100mg/5ml oral suspension sugar free
Take two 5ml spoonfuls three times a day when required for the relief of pain or high temperature. Do not exceed the stated dose.
Supply 300 ml.
Age: from 7 years to 9 years 11 months
NHS cost: £4.64
OTC cost: £8.18
Licensed use: yes
Age from 10 years to 11 years 11 months
Ibuprofen s/f susp: 300mg three times a day
Ibuprofen 100mg/5ml oral suspension sugar free
Take three 5ml spoonfuls three times a day when required for the relief of pain or high temperature. Do not exceed the stated dose.
Supply 300 ml.
Age: from 10 years to 11 years 11 months
NHS cost: £4.64
OTC cost: £8.18
Licensed use: yes

1st line antibiotic: high-dose amoxicillin for 7 days

Age from 1 month to 11 months
Amoxicillin s/f suspension: 125mg three times a day
Amoxicillin 125mg/5ml oral suspension sugar free
Take one 5ml spoonful three times a day for 7 days.
Supply 100 ml.
Age: from 1 month to 11 months
NHS cost: £2.46
Licensed use: yes
Age from 1 year to 4 years 11 months
Amoxicillin s/f suspension: 250mg three times a day
Amoxicillin 250mg/5ml oral suspension sugar free
Take one 5ml spoonful three times a day for 7 days.
Supply 100 ml.
Age: from 1 year to 4 years 11 months
NHS cost: £2.78
Licensed use: yes
Age from 5 years to 11 years 11 months
Amoxicillin s/f suspension: 500mg three times a day
Amoxicillin 250mg/5ml oral suspension sugar free
Take two 5ml spoonfuls three times a day for 7 days.
Supply 200 ml.
Age: from 5 years to 11 years 11 months
NHS cost: £5.56
Licensed use: yes

Penicillin allergy: macrolide for 7 days

Age from 1 month to 1 year 11 months
Erythromycin s/f suspension: 250mg four times a day
Erythromycin ethyl succinate 250mg/5ml oral suspension sugar free
Take one 5ml spoonful four times a day for 7 days.
Supply 200 ml.
Age: from 1 month to 1 year 11 months
NHS cost: £5.68
Licensed use: yes
Age from 1 month to 3 years
Clarithromycin suspension: child weighs 7.9kg or less
Clarithromycin 125mg/5ml oral suspension
*WEIGHT REQUIRED* Take 7.5mg per kg bodyweight TWICE a day for 7 days.
Supply 70 ml.
Age: from 1 month to 3 years
NHS cost: £5.58
Licensed use: yes
Age from 3 months to 5 years
Clarithromycin suspension: child weighs 8kg to 11.9 kg
Clarithromycin 125mg/5ml oral suspension
Take 2.5ml twice a day for 7 days.
Supply 70 ml.
Age: from 3 months to 5 years
NHS cost: £5.58
Licensed use: yes
Age from 6 months to 7 years
Clarithromycin suspension: child weighs 12kg to 19.9kg
Clarithromycin 125mg/5ml oral suspension
Take one 5ml spoonful twice a day for 7 days.
Supply 70 ml.
Age: from 6 months to 7 years
NHS cost: £5.58
Licensed use: yes
Age from 2 years to 11 years 11 months
Erythromycin s/f suspension: 500mg four times a day
Erythromycin ethyl succinate 500mg/5ml oral suspension sugar free
Take one 5ml spoonful four times a day for 7 days.
Supply 200 ml.
Age: from 2 years to 11 years 11 months
NHS cost: £11.10
Licensed use: yes
Age from 3 to 10 years
Clarithromycin suspension: child weighs 20kg to 29.9kg
Clarithromycin 125mg/5ml oral suspension
Take 7.5ml twice a day for 7 days.
Supply 140 ml.
Age: from 3 years to 10 years
NHS cost: £11.16
Licensed use: yes
Age from 7 years to 11 years 11 months
Clarithromycin suspension: child weighs 30kg or more
Clarithromycin 250mg/5ml oral suspension
Take one 5ml spoonful twice a day for 7 days.
Supply 70 ml.
Age: from 7 years to 11 years 11 months
NHS cost: £11.16
Licensed use: yes

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