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Dyspepsia - pregnancy-associated - Management
What drug treatment should I prescribe?

  • Antacids or alginates are recommended as first-line treatments if symptoms are relatively mild and are not controlled adequately by lifestyle changes.
    • Antacid products containing combinations of aluminium and magnesium are recommended on an 'as required' basis.
    • Calcium-containing products are recommended for short-term or occasional use.
    • Alginate products are particularly useful if symptoms of gastro-oesophageal reflux are dominant.
  • If symptoms are severe, or persist despite treatment with an antacid or alginate, consider prescribing an acid-suppressing drug:
    • Ranitidine is an established drug but is not licensed for use in pregnancy.
    • Omeprazole is a more effective alternative. It is licensed for use in pregnancy, but there is less experience of its use in this context.

In depth

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