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Dyspepsia - unidentified cause - Management
Which proton pump inhibitor should I prescribe?
- Five proton pump inhibitors (PPIs) are currently available in the UK: esomeprazole (an isomer of omeprazole), lansoprazole, omeprazole, pantoprazole, and rabeprazole.
- Differences between the PPIs in terms of clinical efficacy and safety are minimal [Aronson, 2006; MeReC, 2006].
- Of the five PPIs available, lansoprazole and omeprazole are both available generically and are considerably cheaper than other PPIs.
- For the eradication of Helicobacter pylori, evidence indicates omeprazole and lansoprazole are equally effective and are as effective as other PPIs.
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