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Dyspepsia - unidentified cause - Management
What dose of proton pump inhibitor should I prescribe?
- Recommended doses of proton pump inhibitors are outlined in Table 1.
Table 1. CKS-recommended proton pump inhibitor (PPI) doses for dyspeptic symptoms that have not been investigated by endoscopy.
PPI | Full dose | Low dose | Helicobacter pylori eradication regimen dose |
|---|
Omeprazole | 20 mg once a day | 10 mg once a day | 20 mg twice a day |
Lansoprazole | 30 mg once a day | 15 mg once a day | 30 mg twice a day |
Pantoprazole | 40 mg once a day | 20 mg once a day | 40 mg twice a day |
Rabeprazole | 20 mg once a day | 10 mg once a day | 20 mg twice a day |
Esomeprazole | 20 mg once a day† | Not available | 20 mg twice a day |
† When undertaking meta-analysis of dose-related effects, NICE classed esomeprazole 20 mg as a full-dose equivalent to omeprazole 20 mg. |
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