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Dyspepsia - unidentified cause - Management
How do I manage dyspepsia in someone with alarm features?

  • For people with dyspepsia and significant acute gastrointestinal bleeding arrange immediate admission to hospital.
  • For all other people with dyspepsia and alarm features:
    • Arrange endoscopy within 14 days and do a full blood count.
    • Suspend nonsteroidal anti-inflammatory drugs while awaiting referral. Offer alternative analgesics (e.g. paracetamol and/or opioids).
    • The management of other drugs will depend on clinical judgement of the benefits and risks of continued treatment. When there is uncertainty seek specialist advice. Management options include:
      • Stopping the drug.
      • Reducing the frequency or dose of the drug.
      • Substituting the drug for one less likely to cause bleeding or dyspepsia.
    • Review and manage lifestyle factors known to exacerbate dyspepsia.
    • Prescribe either an alginate or an antacid to relieve dyspepsia whilst awaiting endoscopy. Ensure that proton pump inhibitors or H2-receptor antagonists (including those obtained over-the-counter) are not used, for a minimum of 2 weeks, before endoscopy.
    • Advise those people who deteriorate significantly to seek medical attention.

In depth

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