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Endometriosis - Management
Progestogens

Age from 16 to 60 years
Medroxyprogesterone acetate 150mg syringe (Depo-Provera®)
Medroxyprogesterone 150mg/1ml suspension for injection pre-filled syringes
Give 150mg (1ml) by deep intramuscular injection.
Supply 1 1ml prefilled syringe.
Age: from 16 years to 60 years
NHS cost: £5.01
Licensed use: yes
Patient information: You may experience altered bleeding patterns whilst you are using this injection.
Levonorgestrel 20mcg/24hrs intra-uterine system (Mirena®)
Levonorgestrel 20micrograms/24hours intrauterine system
For insertion into the uterine cavity.
Supply 1 device.
Age: from 16 years to 60 years
NHS cost: £83.16
Licensed use: yes
Patient information: You may experience irregular bleeding for about 6 months after insertion of the device. Seek medical advice if this persists.
Desogestrel 75micrograms (Cerazette®)
Cerazette 75microgram tablets
Take one tablet once a day. See package insert for full instructions.
Supply 84 tablets.
Age: from 16 years to 60 years
NHS cost: £8.85
Licensed use: yes
Patient information: Take the pill at the same time each day. If you forget a pill, take it as soon as you remember, and the next one at your normal time. If you are more than 12 hours late with any Cerazette pill, it may not work. Take it as soon as you remember, and the next one at your normal time. You must use an extra contraceptive method for the next 2 days (48 hours) or you may become pregnant. You should also do this if you vomit within 2 hours of taking the pill or if you have very severe diarrhoea.
Etonogestrel 68mg implant (Nexplanon®)
Etonogestrel 68mg implant
For subdermal implantation.
Supply 1 implant.
Age: from 16 years to 60 years
NHS cost: £90.00
Licensed use: yes
Age from 16 years onwards
Medroxyprogesterone: 10mg three times a day (not contraceptive)
Medroxyprogesterone 10mg tablets
Take one tablet three times a day.
Supply 90 tablets.
Age: from 16 years onwards
NHS cost: £22.16
Licensed use: yes
Patient information: Begin the course of tablets on the first day of your period. Use a non-hormonal (barrier) contraception method whilst you are taking these tablets.
Norethisterone tablets: 5mg twice a day (not contraceptive)
Norethisterone 5mg tablets
Take one tablet twice a day.
Supply 60 tablets.
Age: from 16 years onwards
NHS cost: £5.22
Licensed use: yes
Patient information: Begin the course of tablets on the fifth day of your period. If 'spotting' occurs and does not settle within a few weeks, you may increase to 4 or 5 tablets daily, but reduce to 2 tablets daily once this bleeding between periods has stopped. Use a non-hormonal (barrier) contraception method whilst you are taking these tablets.

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