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CKS is no longer commissioned by the National Institute for Health and Clinical Excellence (NICE). NICE remains committed to providing a replacement service for CKS and is currently reviewing its options. In the meantime, although CKS content is now not being maintained, it still remains relevant and will continue to be made available. CKS content was generated under a programme of topic creation and update. To check if the topic you are viewing is current or out of date, please refer to the topic publication details by clicking on the 'How up-to-date is this topic?' link in the left hand menu on individual topic pages.

Fungal nail infection (onychomycosis) - Evidence
Evidence on treatments for dermatophyte onychomycosis

  • This section reviews the evidence on treatments for dermatophyte onychomycosis.
  • CKS has included, where available, evidence on fingernail onychomycosis, although systematic reviews have focussed on toenail onychomycosis [Crawford et al, 2002; Crawford and Ferrari, 2007; Crawford and Hollis, 2007]. There is no important reason, apart from duration of treatment, why evidence on the effectiveness on treatments for toenail onychomycosis cannot be generalized to fingernail onychomycosis.
  • CKS has not reviewed evidence on drug treatments that are not licensed in the UK.
  • Evidence on two herbal treatments promoted for fungal nail infection has been reviewed.

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