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Gonorrhoea - Management
How do I make a diagnosis in women?
- Uncomplicated gonorrhoea causes no symptoms in up to 50% of women.
- Where present, symptoms usually develop within 10 days.
- Genital infection is most common and causes:
- Increased or altered vaginal discharge in up to 50% of women.
- Pain or difficulty urinating (dysuria) in 12% of women. Urgency or frequency are uncommon.
- Intermenstrual bleeding, sometimes triggered by intercourse (less commonly).
- Pelvic or abdominal pain, with possible pain on intercourse (dyspareunia), if there is ascending infection (see the CKS topic on Pelvic inflammatory disease).
- Rectal gonorrhoea may occur, but tends to cause symptoms (anal pruritus, pain and spasm of the anal sphincter [tenesmus], purulent discharge, or bleeding) that are less severe than in men.
- Pharyngeal infection is asymptomatic in 90% of women, but it may cause overt pharyngitis.
- Examination may show:
- Most commonly, purulent or mucopurulent endocervical discharge, or easily induced endocervical bleeding. However, this is not a sensitive predictor of cervical infection (occurring in less than 50% of women).
- Less commonly, purulent discharge from the urethra.
- Abdominal tenderness if pelvic inflammatory disease is present.
- Diagnosis of gonorrhoea is confirmed by positive identification of Neisseria gonorrhoeae through culture, which requires an endocervical swab.
- Nucleic acid amplification tests, which require a first-pass urine sample, may also be used initially depending on local protocols, although culture will also usually be required for confirmation.
- See the CKS topic on Vaginal discharge for further information.
[BASHH, 2005b; Handsfield and Sparling, 2005; Bignell et al, 2006]
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