CKS is no longer commissioned by the National Institute for Health and Clinical Excellence (NICE). NICE remains committed to providing a replacement service for CKS and is currently reviewing its options. In the meantime, although CKS content is now not being maintained, it still remains relevant and will continue to be made available. CKS content was generated under a programme of topic creation and update. To check if the topic you are viewing is current or out of date, please refer to the topic publication details by clicking on the 'How up-to-date is this topic?' link in the left hand menu on individual topic pages.
Gout - Management
What dosing regimen of intra-articular corticosteroid should I use?
- Intra-articular corticosteroids are not specifically licensed in the treatment of gout.
- The licensed dose of intra-articular injection depends upon the steroid chosen, size of the joint, and the severity of the condition.
- Methylprednisolone: 40–80 mg (1–2 mL) for large joints, 20–40 mg (0.5–1 mL) for medium joints, 10–20 mg (0.25–0.5 mL) for small joints.
- Triamcinolone acetonide: 40 mg (1 mL) for large joints, 20–40 mg (0.5–1 mL) for medium joints.
- Hydrocortisone acetate: 12.5–25 mg (0.5–1 mL) for small joints.
© NHS Institute for Innovation and Improvement