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Herpes simplex - genital - Background information
What is it?
- A first episode of genital herpes presents with multiple painful blisters, which quickly burst to leave erosions and ulcers, on the external genitalia (as well as on the cervix, rectum, thighs, and buttocks). Lesions are usually bilateral and develop 4–7 days after exposure to herpes simplex virus (HSV) infection [Kimberlin and Rouse, 2004]. People may complain of dysuria, vaginal or urethral discharge, and systemic symptoms such as fever and malaise. A primary episode can last up to 20 days, and is often more severe than a recurrent episode [Gupta et al, 2007; BASHH, 2007].
- Recurrent genital herpes refers to a recurrence of clinical symptoms due to reactivation of pre-existent HSV infection, after a latent period. People typically present with painful blisters or ulcers unilaterally in a single anatomical site, and prodromal tingling and burning symptoms may precede the development of lesions by hours or days. Systemic symptoms such as fever and malaise are less common than initial episodes, and recurrent attacks are usually less severe, lasting between 5–10 days [Gupta et al, 2007].
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