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Hypercholesterolaemia - familial - Management
Basis for recommendation

These recommendations are in line with a guideline published by the National Institute for Health and Clinical Excellence (NICE), Identification and management of familial hypercholesterolaemia [NICE, 2008].

  • The recommendation to consider checking blood glucose and renal function is extrapolated from guidelines for people with non-familial dyslipidaemia, including a NICE guideline, Lipid modification: cardiovascular risk assessment and the modification of blood lipids for the primary and secondary prevention of cardiovascular disease [National Collaborating Centre for Primary Care, 2008a]; the Scottish Intercollegiate Guidelines Network (SIGN) guideline Risk estimation and the prevention of cardiovascular disease [SIGN, 2007]; and the Joint British Societies' guidelines on prevention of cardiovascular disease in clinical practice [British Cardiac Society et al, 2005].
    • The identification of additional risk factors for coronary heart disease will guide the management (in particular, referral) of adults with familial hypercholesterolaemia.

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