Version 1.10, revision planned in 2012.
Last revised in February 2008
November 2010 — minor update. From October 2010, the Joint Committee on Vaccination and Immunisation recommended that the vaccines currently given at 12 months (Hib/MenC) and 13 months of age (MMR, PCV) should be given at the same visit, between 12 and 13 months of age, to simplify the routine childhood immunisation schedule [CMO, 2010]. Issued in November 2010.
October 2010 — technical update. The management section of this topic has been simplified to improve clarity and navigation. There have been no changes to the clinical content or meaning of the recommendations.
March 2010 — minor update. Prevenar® has been replaced by Prevenar 13® [Salisbury, 2010]. Issued March 2010.
May 2009 — minor update. The Hib catch-up programme ceased on 3 March 2009. The pre-school booster has now reverted to DTaP/IPV (Infanrix-IPV®) or dTaP/IPV (Repevax®). This topic has been updated accordingly. Issued in June 2009.
January 2009 — minor update. Information from the Rapid Response Report from the National Patient Safety Agency added, regarding the risks of omitting Hib when administering Infanrix-IPV+Hib®, if the powdered Hib component is not reconstituted using the contents of the pre-filled syringe [NPSA, 2008]. Issued in February 2009.
October 2007 to February 2008 — converted from PRODIGY guidance to CKS topic structure. The evidence-base has been reviewed in detail, and recommendations are more clearly justified and transparently linked to the supporting evidence.
There are no major changes to the recommendations. This topic has been updated from the guidelines published by the Department of Health, Immunisation against infectious diseases ('Green Book').