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Immunizations - travel vaccinations - Management
What are the adverse effects of Japanese encephalitis vaccine?

Green Cross® vaccine

  • Japanese encephalitis vaccine is associated with a moderate frequency of local and mild systemic adverse effects. They occur in 10–20% of recipients.
  • Serious systemic reactions (urticaria, angio-oedema, and cardiovascular collapse), occur in about 0.6% of vaccine recipients. Most systemic reactions occur within the first few minutes of vaccination, but may occur up to 2 weeks after vaccination.
  • Rare neurological events including encephalitis have also been reported (1–2.3 cases per million recipients).

[ABPI Medicines Compendium, 2004b; NaTHNaC, 2008]

IXIARO® vaccine

  • Adverse effects are common (reported in up to 40% of participants in clinical trials) but are usually mild and disappear within a few days.
  • Headache (20%) and myalgia (13%) were most commonly reported.

[ABPI Medicines Compendium, 2009]

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