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Immunizations - travel vaccinations - Management
What schedule is used for typhoid fever vaccine?
- Maximum antibody response to the inactivated typhoid vaccine is achieved 1 month after vaccination and persists for about 3 years.
Table 1. Schedule for the inactivated typhoid vaccine.
Vaccine | Schedule | Length of protection | Age |
|---|
Typhim Vi® | Single dose. | 3 years. | Adults and children 2 years and older. |
Typherix® | Single dose. | 3 years. | Adults and children 2 years and older. |
ViATIM®(combined hepatitis A and typhoid vaccine) | Single dose of combined vaccine. | Typhoid Revaccination with single dose purified polysaccharide typhoid vaccine every 3 years. Hepatitis A Booster dose of inactivated hepatitis A vaccine after 6–12 months. | From 16 years. |
Hepatyrix®(combined hepatitis A and typhoid vaccine) | Single dose of combined vaccine. | Typhoid Revaccination with single dose purified polysaccharide typhoid vaccine every 3 years. Hepatitis A Booster dose of inactivated hepatitis A vaccine after 6–12 months. | From 15 years. |
|
Basis for recommendation
- The inactivated typhoid vaccine may be preferred to the oral live vaccine as it:
- Can be administered as a single dose (the oral vaccine is administered as 3 doses).
- Protects against typhoid infection for 3 years (oral vaccine only protects for 1 year).
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