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Lipid modification - primary and secondary CVD prevention - Management
What are the cautions and contraindications for fibrates?
- Do not prescribe a fibrate in people who have, or have had:
- Severe hepatic impairment (including biliary cirrhosis).
- Severe renal impairment.
- Gallbladder disease.
- Known photoallergy or phototoxic reaction during treatment with a fibrate.
- Chronic or acute pancreatitis with the exception of acute pancreatitis due to severe hypertriglyceridemia.
- Pregnancy and lactation.
[ABPI Medicines Compendium, 2006b; ABPI Medicines Compendium, 2007b; ABPI Medicines Compendium, 2007d; ABPI Medicines Compendium, 2007e; ABPI Medicines Compendium, 2008b]
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