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Lipid modification - primary and secondary CVD prevention - Management
What is the mechanism of action of fibrates?
- The mechanism of action of fibrates is complex; they are thought to:
- Reduce plasma triglycerides by inhibiting their hepatic synthesis and increasing their catabolism.
- Increase high-density lipoprotein cholesterol by increasing apoA-I and apoA-II gene transcription.
[Aronson, 2006a]
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