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Lipid modification - primary and secondary CVD prevention - Management
Which first-line lipid modification therapy is recommended for secondary prevention?

  • Prescribe a statin, unless this is contraindicated.
  • Simvastatin 40 mg daily is the first-line choice.
  • Consider a lower dose of simvastatin or an alternative statin (e.g. pravastatin 40 mg daily) if there are potential drug interactions or simvastatin 40 mg is contraindicated.
  • Higher intensity statin therapy (simvastatin 80 mg or atorvastatin 80 mg) should only be considered first-line for people with acute coronary syndrome. Treatment should be initiated in secondary care.

In depth

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