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Lipid modification - primary and secondary CVD prevention - Management
Nicotinic acid

Age from 18 years onwards
Nicotinic acid tablets: initiation pack
Niaspan titration pack
Follow the instructions given inside this pack.
Supply 21 tablets.
Age: from 18 years onwards
NHS cost: £14.00
Licensed use: no - off-label indication
Patient information: Take 375 mg once daily at night (after a low-fat snack) for 1 week, then 500 mg once daily at night for 1 week, then 750 mg once daily at night for 1 week. Seek urgent medical advice if you develop unexplained muscle pain, weakness or cramps and stop treatment until this has been investigated.
Nicotinic acid m/r tablets: 1000mg daily (maintenance)
Nicotinic acid 500mg modified-release tablets
Take two tablets at bedtime.
Supply 56 tablets.
Age: from 18 years onwards
NHS cost: £17.25
Licensed use: no - off-label indication
Patient information: Take the tablets at bedtime, after a low-fat snack (e.g. an apple, low fat yoghurt, slice of bread). Avoid drinking alcohol or hot drinks at the same time as taking the tablets as this may increase undesirable flushing and itching. Seek urgent medical advice if you develop unexplained muscle pain, weakness or cramps and stop treatment until this has been investigated.
Nicotinic acid m/r tablets: 1500mg daily (maintenance)
Nicotinic acid 750mg modified-release tablets
Take two tablets at bedtime.
Supply 56 tablets.
Age: from 18 years onwards
NHS cost: £26.25
Licensed use: no - off-label indication
Patient information: Take the tablets at bedtime, after a low-fat snack (e.g. an apple, low fat yoghurt, slice of bread). Avoid drinking alcohol or hot drinks at the same time as taking the tablets as this may increase undesirable flushing and itching. Seek urgent medical advice if you develop unexplained muscle pain, weakness or cramps and stop treatment until this has been investigated.
Nicotinic acid m/r tablets: 2000mg daily (maintenance)
Nicotinic acid 1g modified-release tablets
Take two tablets at bedtime.
Supply 56 tablets.
Age: from 18 years onwards
NHS cost: £34.75
Licensed use: no - off-label indication
Patient information: Take the tablets at bedtime, after a low-fat snack (e.g. an apple, low fat yoghurt, slice of bread). Avoid drinking alcohol or hot drinks at the same time as taking the tablets as this may increase undesirable flushing and itching. Seek urgent medical advice if you develop unexplained muscle pain, weakness or cramps and stop treatment until this has been investigated.

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