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Lower urinary tract symptoms in men, age-related (including symptoms of benign prostatic hyperplasia/hypertrophy) - Management
Second-line antimuscarinics: if oxybutynin not tolerated (LUTS)

Age from 40 years onwards
Start oxybutynin m/r tablets: 5mg once a day
Oxybutynin 5mg modified-release tablets
Take one tablet once a day.
Supply 30 tablets.
Age: from 40 years onwards
NHS cost: £10.81
Licensed use: yes
Start oxybutynin patches: apply one patch twice a WEEK
Oxybutynin 3.9mg/24hours patches
Apply one patch twice a week.
Supply 8 patches.
Age: from 40 years onwards
NHS cost: £27.20
Licensed use: yes
Patient information: Apply to clean, dry, unbroken skin on the abdomen, hip, or buttock. Remove after 3–4 days and apply a new patch on a different area (avoid using the same area for 7 days).
Start tolterodine m/r capsules: 4mg once a day
Tolterodine 4mg modified-release capsules
Take one capsule once a day.
Supply 28 capsules.
Age: from 40 years onwards
NHS cost: £25.78
Licensed use: yes
Start tolterodine tablets: 2mg twice a day
Tolterodine 2mg tablets
Take one tablet twice a day.
Supply 56 tablets.
Age: from 40 years onwards
NHS cost: £30.56
Licensed use: yes
Start trospium tablets: 20mg twice a day
Trospium chloride 20mg tablets
Take one tablet twice a day (on an empty stomach).
Supply 60 tablets.
Age: from 40 years onwards
NHS cost: £26.00
Licensed use: yes
Start trospium m/r capsules: 60mg once a day
Trospium chloride 60mg modified-release capsules
Take one capsule once a day.
Supply 28 capsules.
Age: from 40 years onwards
NHS cost: £23.05
Licensed use: yes
Start darifenacin m/r tablets: 7.5mg once a day
Darifenacin 7.5mg modified-release tablets
Take one tablet once a day.
Supply 28 tablets.
Age: from 40 years onwards
NHS cost: £20.90
Licensed use: yes
Black triangle
Start fesoterodine m/r tablets: 4mg once a day
Fesoterodine 4mg modified-release tablets
Take one tablet once a day.
Supply 28 tablets.
Age: from 40 years onwards
NHS cost: £25.78
Licensed use: yes
Black triangle
Patient information: Do NOT eat or drink products containing grapefruit juice whilst taking this medicine.
Start solifenacin tablets: 5mg once a day
Solifenacin 5mg tablets
Take one tablet once a day.
Supply 28 tablets.
Age: from 40 years onwards
NHS cost: £27.62
Licensed use: yes
Start propiverine tablets: 15mg 2 to 3 times a day
Propiverine 15mg tablets
Take one tablet two to three times a day.
Supply 84 tablets.
Age: from 40 years onwards
NHS cost: £27.00
Licensed use: yes
Start propiverine m/r capsules: 30mg once a day
Propiverine 30mg modified-release capsules
Take one capsule once a day.
Supply 28 capsules.
Age: from 40 years onwards
NHS cost: £24.45
Licensed use: yes

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