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CKS is no longer commissioned by the National Institute for Health and Clinical Excellence (NICE). NICE remains committed to providing a replacement service for CKS and is currently reviewing its options. In the meantime, although CKS content is now not being maintained, it still remains relevant and will continue to be made available. CKS content was generated under a programme of topic creation and update. To check if the topic you are viewing is current or out of date, please refer to the topic publication details by clicking on the 'How up-to-date is this topic?' link in the left hand menu on individual topic pages.

Previous updates

From NHS Evidence:

Recent annual evidence updates listed on the CKS website

Parkinson's disease: 14th - 18th February

From NHS Evidence - neurological conditions

  • The Neurological Conditions Specialist Collection is launching its second Annual Evidence Update on Parkinson’s Disease on Monday 14 February 2011.
  • The Neurological Conditions Specialist Collection Project Team has carried out a systematic literature search on Parkinson’s Disease (PD) to identify all high level evidence published since the date of the last searches for the Parkinson’s Disease guideline published by SIGN in January 2010. Leading PD experts from around the UK have read and appraised the evidence for its validity and relevance to the busy clinician.
  • A list of the papers deemed worthy of inclusion, along with expert commentaries by our reviewers, will be freely available on the site at www.library.nhs.uk/neurological from 14 February. This year we have continued to identify uncertainties in research to contribute to the DUETs project (see www.library.nhs.uk/duets for more details).

Tinnitus: 7th - 11th February

From NHS Evidence - ENT and audiology

  • The Annual Evidence Update on Tinnitus will be published on 7 February with the aim of presenting relevant systematic reviews and guidance from the past 12 months, in addition to highlighting therapeutic uncertainties where research gaps exist

Patient and carer involvement in chronic disease: 17 January 2011

From NHS Evidence - supportive and palliative care.

This is the third evidence update on patient and carer engagement in chronic disease management and we have continued to broaden the scope of the literature we accessed, in order to reflect the widening field of supportive and end of life care.

Urinary incontinence: 31 January 2011

From NHS Evidence - kidney diseases and male urogenital disorders.

The Kidney Diseases and Male Urogenital Disorders Specialist Collection and the Women's Health Specialist Collection have identified and reviewed new evidence on the diagnosis and management of urinary incontinence published during the last 12 months. The Kidney Diseases and Male Urogenital Disorders Specialist Collection presents evidence published since the release of the NICE guideline on Lower Urinary Tract Symptoms which has been reviewed by urologists from the Churchill Hospital in Oxford.

Urinary incontinence: 31 January 2011

From NHS Evidence - women's health.

The Women's Health Specialist Collection provides an update on the latest evidence on the management of female urge urinary incontinence/overactive bladder and the pharmacotherapy, surgical and conservative management of female stress urinary incontinence.

CAM for lower back pain: 13-17 December 2010

From NHS Evidence - complementary and alternative medicine.

Including a list of systematic reviews, meta-analyses and selected randomised controlled trials, along with commentaries from experts.

Familial hypercholesterolaemia: 13-17 December 2010

From NHS Evidence - genetic conditions.

Including a list of relevant guidelines, systematic reviews, meta-analyses and selected randomised controlled trials published in the last year, together with a commentary written by a relevant expert.

Headache: 13-17 December 2010

From NHS Evidence - neurological conditions.

Including guidelines, systematic reviews, health technology assessments and economic evaluations, along with expert commentaries, and uncertainties in research to contribute to the DUETs database

Alcoholic liver disease: 6-10 December 2010

From NHS Evidence - gastroenterology and liver diseases.

Alcohol misuse produces a spectrum of liver injury ranging from simple fatty change through alcoholic hepatitis to cirrhosis and, in some 20% of individuals, to hepatocellular carcinoma. We will be presenting an overview of the best systematic reviews from the past year, along with commentaries from experts in the field. We will also provide links to useful policy documents and other items of interest.

Malignancies post kidney transplant: 6-10 December 2010

From NHS Evidence - kidney diseases and male urogenital disorders.

Systematic reviews, randomised controlled trials and cohort studies on post-transplant lymphoproliferative disease (PTLD), published since the introduction of the BSH/BTS guidelines for the diagnosis and management of PTLD in June 2010.

HIV/AIDS: 30 November - 3 December 2010

From NHS Evidence - infections and NHS Evidence - National Library for Public Health.

Coinciding with World AIDS Day on 1 December, focussing on HIV and TB co-infection, and behaviour change in high-risk populations.

Expert commentaries include:

  • The global overview of HIV and TB co-infection
  • An overview of the BHIVA guidelines for treatment of HIV and TB co-infection
  • Clinical implications of HIV and TB co-infection for GPs
  • An overview of HIV and TB co-infection in the UK
  • Diagnostic tests and guidelines
  • Behaviour change interventions in high-risk populations including ethnic minorities, gay men, injecting drug users, commercial sex workers, and other populations.

Special care dentistry: 30 November - 3 December 2010

From NHS Evidence - oral health.

Coinciding with meetings of the two professional societies for special care dentistry (British Society for Disability and Oral Health and British Society of Gerodontology).

Stroke: 30 November - 3 December 2010

From NHS Evidence - stroke.

Focussing on stroke rehabilitation, including organisation of care, upper limbs, mobility, speech and language, basic personal needs, cognition and perception and living with stroke. There will also be a section on uncertainties identified and expert summaries.

Glaucoma: 22-26 November 2010

From NHS Evidence - eyes and vision.

An update on:

  • Diagnosis,
  • Monitoring/follow up,
  • Treatment (medical, surgical and laser),
  • Patient education,
  • Service provision,
  • Routine NHS information.

Supportive and palliative care in chronic lung disease: 22-26 November 2010

From NHS Evidence - supportive and palliative care.

Focussing on:

  • Dyspnoea (or breathlessness) - usually one of the most prevalent in surveys of problems associated with respiratory and other systemic illnesses.
  • Cough - less common but can nevertheless be just as distressing for patients with cancer and other chronic conditions.

COPD: 15-19 November 2010

From NHS Evidence - respiratory.

  • Published to coincide with World COPD Day on 17 November 2010.

End of life care: 15-19 November 2010

From NHS Evidence - commissioning and NHS Evidence - innovation and improvement.

Up-to-date knowledge and evidence on issues related to the quality of care for those approaching the end of their life and their carers. Areas to be covered are:

  • Measuring quality
  • Access to care
  • Patient experience, including communication
  • Pathways
  • Carers, including bereavement and after death care
  • Policy and professional organisation documents.

Lung cancer: 15-19 November 2010

From NHS Evidence - cancer.

With a guest editorial, expert commentaries, systematic reviews and guidance that have been published since November 2009, on:

  • Causes, risks and prevention
  • Screening
  • Assessment and diagnosis
  • Treatment and disease management
  • Service delivery and standards.

Diabetes: 8-12 November 2010

From NHS Evidence - diabetes.

New relevant systematic reviews, classified under: co-morbidities, complications, condition management, delivery of care, diagnosis/classification, economics, ethnicity, epidemiology, genetics, gestational diabetes, living with diabetes, other types of diabetes, patient education, pre-diabetic state, pregnancy, prevention/causes/risk factors, and screening. Overall commentary from Dr Roger Gadsby, and expert commentaries on diabetes nursing, diabetic nephropathy and dietetics.

Head and neck cancer: 1-5 November 2010

From NHS Evidence - cancer, NHS Evidence - ENT and audiology and NHS Evidence - oral health.

Including key guidance and quality appraised systematic reviews published since the SIGN guidance, combined with expert commentaries on the following topics:

  • Causes, risks and prevention
  • Screening
  • Assessment and diagnosis
  • Treatment and disease management
  • Service delivery and standards.

Additional therapeutic uncertainties will highlight research gaps and there will be links to relevant high quality patient information.

Psoriasis: 1-5 November 2010

From NHS Evidence - skin disorders.

New national guidance and systematic reviews, and a 'what's new' analysis, discussing the new evidence and its implications for clinical practice — by Dr Amy Foulkes, Professor Chris Griffiths and Dr Richard Warren.

NHS service reconfiguration: 25-29 October 2010

From NHS Evidence - health management.

Up-to-date knowledge and evidence about several aspects of service reconfiguration, including those that affect several clinical specialisms.

Ethnicity: 18-22 October 2010

From NHS Evidence - ethnicity and health.

The ethnicity and health specialist collection's annual evidence update will take place later this week, with all articles included being written by experts in the field and quality assured. This year's topics include:

  • Breast Cancer
  • Refugee Health
  • Black and Minority Ethnic Carers
  • End of Life Care
  • Childhood Heart Risk Factors

Breast Cancer: 11-15 October 2010

From NHS Evidence - cancer.

Including systematic reviews and guidance.

CAM for Depression: 4-8 October 2010

From NHS Evidence - complementary and alternative medicine.

Presenting the evidence on specific therapies and approaches such as acupuncture, diet and nutrition, herbal medicine, massage, meditation and mindfulness, and yoga.

Heart failure: 4-8 October 2010

From NHS Evidence - cardiovascular.

Following the partial update of NICE's Heart Failure guidelines in August 2010. Topics include diagnosis, pharmacology, organisation of care, devices, rehabilitation, palliative care and psychology. There will also be a section on uncertainties identified and expert summaries.

Osteoarthritis: 20-24 September 2010

From NHS Evidence - musculoskeletal and NHS Evidence - trauma and orthopaedics.

The results of a search for new national guidance and systematic reviews published since August 2009, with commentaries discussing the new evidence.

Surgical Aspects of Faecal Incontinence: 20-24 September 2010

From NHS Evidence - surgery, anaesthesia, perioperative and critical care.

Coinciding with National Continence Awareness Week 2010. NICE guidance on faecal incontinence (CG49) was published in June 2007 based on literature published prior to October 2006. This update highlights relevant, good quality evidence, focusing specifically on surgical management (including biofeedback and implants).

Alzheimer's disease and dementia: 13-17 September 2010

From NHS Evidence - later life.

Providing healthcare professionals with a clear path to the most important recent evidence surrounding the five major types of dementia: alzheimer's, vascular dementia, dementia with lewy bodies, frontotemporal dementia and mixed dementias. Providing bibliographies on secondary research (systematic reviews, meta analyses and guidelines) on the following topics:

  • Definitions, Diagnosis and Screening
  • Risk Factors and Aetiology
  • Pharmacological Treatments
  • Non-Pharmacological Treatments
  • Models of Dementia Care
  • Evidence on Other Dementias

Diabetic retinopathy: 13-17 September 2010

From NHS Evidence - diabetes.

Diabetic retinopathy is the most common cause of blindness in working age people in the UK. Information is organised by topic areas and links are provided within each topic to the relevant systematic reviews, primary research, guidelines and patient information. Topics include: incidence and prevalence of DR, epidemiology and progression of DR, factors influencing development of DR, screening for DR, treatment, surgery, modern therapies, blindness and visual impairment, and assessment of retinopathy by automated computer algorithm.

Eczema: 13-17 September 2010

From NHS Evidence - skin disorders.

Discussing new evidence and its implications for clinical practice — this year written by Professor Hywel Williams and Dr Kave Shams.

Epilepsy: 6-10 September 2010

From NHS Evidence - neurological conditions.

Including guidelines, systematic reviews, health technology assessments and economic evaluations. Leading epilepsy experts from around the UK have read and appraised these for their validity and relevance.

Gastrointestinal symptoms in supportive and palliative care: 6-10 September 2010

From NHS Evidence - supportive and palliative care.

Focussing on the best new evidence on treatments for anorexia and cachexia in chronic disease and palliative care.

Hepatitis B and C: 26-30 July 2010

From NHS Evidence - gastroenterology and liver diseases.

High level evidence including guidelines, systematic reviews, health technology assessments and economic evaluations. Leading experts from around the UK have read and appraised these for their validity and relevance to the busy clinician, with expert commentary.

Hip fracture: 26-30 July 2010

From NHS Evidence - trauma and orthopaedics and NHS Evidence - emergency and urgent care.

This Annual Evidence Update will appeal to all health professionals, reflecting the multidisciplinary approach required across both primary and secondary care. However, there may be clinicians who are involved in the management of polytrauma and high energy injuries that affect the hip joint who will find that our update is offset from their area of interest.

Health needs of people with learning disabilities: 28 June - 2 July 2010

From NHS Evidence - learning disabilities.

People with learning disabilities have a higher level of health needs than the general population, many of which are unmet. This update will provide bibliographies of published research for the following key health issues:

  • Cancer
  • Challenging behaviour
  • Coronary heart disease
  • Epilepsy
  • Respiratory illness.

Osteoporosis and Fragility Fractures: 21-25 June 2010

From NHS Evidence - musculoskeletal.

Concentrating on systematic reviews, these being the most reliable and least biased evidence available to guide practice and improve knowledge in this area.

Oesophago-gastric Cancer: 21-25 June 2010

From NHS Evidence - cancer and NHS Evidence - gastroenterology and liver diseases.

Including systematic reviews and guidance, clinical commentary by Dr. Jamshed B. Bomanji (on FDG PET) and an overview by Dr Chris Alcock.

Age Related Macular Degeneration: 14-18 June 2010

From NHS Evidence - eyes and vision.

Age Related Macular Degeneration (AMD) is one of the most common causes of certifiable visual impairment in the UK. The 2010 Evidence Update focuses on the management of neovascular (wet) AMD and highlights the:

  • Key evidence base underpinning current interventions (key randomised controlled trials and current guidance).
  • New evidence that is likely to inform a change in clinical practice.
  • Emerging evidence for Lucentis, Avastin and combination treatments from key RCTs that have recently reported at scientific conferences but not yet published in peer reviewed literature.
  • Current uncertainties in the effectiveness of treatments.

Commentaries have been provided by Robin Hamilton, Consultant Ophthalmic Surgeon and Praveen Patel, Consultant Ophthalmologist, Moorfields Eye Hospital NHS Foundation Trust and by Angela Reidy and Darwin Minassian, EpiVision.

Homeopathy: 14-18 June 2010

From NHS Evidence - complementary and alternative medicine.

A summary of systematic reviews, meta-analyses, RCTs and other relevant studies.

Atrial fibrillation: 7-11 June 2010

From NHS Evidence - cardiovascular.

Topics will include medication, cardioversion, prevention of stroke, catheter ablation therapy and surgical treatment. This year we've also identified new systematic reviews on genetics and atrial fibrillation. As usual expert summaries with be included.

Drugs misuse: 7-11 June 2010

From NHS Evidence - National Library for Public Health.

Themed on drugs misuse treatment in offender populations. As well as identifying a number of new guidelines and key policy documents, we have focussed on treatments for female offenders.

Osteoporosis and fragility fractures: 7-11 June 2010

From NHS Evidence - musculoskeletal.

Concentrating on highlighting systematic reviews, to guide practice and improve knowledge in this area.

Menorrhagia: 1-4 June 2010

From NHS Evidence - women's health.

The most up-to-date knowledge on the diagnosis and management of heavy menstrual bleeding.

Proteinuria and estimated glomerular filtration rate: 24-28 May 2010

From NHS Evidence - kidney diseases and male urogenital disorders.

Presenting the highest-quality evidence on the basic science, clinical aspects, and management.

Oral health: 17-21 May 2010

From NHS Evidence - oral health.

Marking the start of National Smile Month 2010 (www.nationalsmilemonth.org). Presenting recently published systematic reviews and guidelines on a range of oral health topics with commentaries from experts in the field.

Cystic fibrosis: 10-14 May 2010

From NHS Evidence - respiratory and NHS Evidence - genetic conditions.

Highlighting major publications and implications for practice, and including updates on Cochrane protocols and reviews needed, as identified by the Cochrane Cystic Fibrosis and Genetic Disorders Group.

Rhinitis: 10-14 May 2010

From NHS Evidence - ENT and audiology.

Multiple databases have been searched to identify relevant guidelines and systematic reviews, which have undergone quality assessment prior to inclusion. Therapeutic uncertainties have also been updated to highlight priority research topics.

Skin cancer: 10-14 May 2010

From NHS Evidence - cancer and NHS Evidence - skin disorders.

Corresponding with Sun Awareness Week. Presenting new guidance and systematic reviews, with expert commentaries discussing the significance of the new evidence.

© NHS Institute for Innovation and Improvement