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Nonsteroidal anti-inflammatory drugs (standard or coxibs) - prescribing issues - Management
Can NSAIDs be used during pregnancy?
- Paracetamol is the analgesic and/or antipyretic of choice during pregnancy.
- However, if during the first or second trimester paracetamol is ineffective and an NSAID is clinically indicated:
- Ibuprofen is the preferred NSAID, but should only be used before 30 weeks of pregnancy (off-label use).
- Use the lowest effective dose for the shortest duration possible.
- If regular use is clinically indicated, such as in a woman with rheumatoid arthritis, seek specialist advice.
- NSAIDs must not be used from 30 weeks of pregnancy onwards without specialist advice and regular fetal monitoring.
For more information, contact the UK Teratology Information Service (UKTIS), formerly the National Teratology Information Service (NTIS), on 0844 892 0909.
In depth
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