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Obesity - Management
What important interactions are associated with orlistat?
- Fat-soluble vitamins or multivitamin supplements: if needed, they should be given at least 2 hours after a dose of orlistat or at bedtime.
- Ciclosporin: if concomitant use is unavoidable, monitor ciclosporin levels frequently, especially when starting or stopping orlistat.
- Warfarin: monitor international normalized ratio (INR) closely, especially when starting or stopping orlistat.
- Levothyroxine: consider giving at least 2 hours after a dose of orlistat or at bedtime.
- Antiepileptic drugs: consider giving at least 2 hours after a dose of orlistat or at bedtime.
In depth
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