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Palliative cancer care - nausea & vomiting - Management
How should I treat nausea and vomiting due to intracranial disease?
- Nausea and vomiting due to intracranial disease: give cyclizine, 25–50 mg every 8 hours and when required (maximum dose 150 mg/24 hours).
- If intracranial pressure is raised:
- Consider referral for radiotherapy for all people with raised intracranial pressure due to a tumour.
- Consider adding high-dose dexamethasone:
- A suitable dose might be 8–16 mg daily for up to 7 days, with subsequent reduction to 4–6 mg daily if possible.
- Stop dexamethasone therapy if there is no obvious benefit within 3–5 days, or if it becomes ineffective.
Basis for recommendation
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