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Palliative cancer care - nausea & vomiting - Management
Metoclopramide or domperidone (oral, rectal, or parenteral)

Age from 16 years onwards
Metoclopramide tablets: 10mg three times/day and when required
Metoclopramide 10mg tablets
Take one tablet three times a day AND when required to relieve nausea and vomiting.
Supply 28 tablets.
Age: from 16 years onwards
NHS cost: £1.00
Licensed use: no - off-label dose
Patient information: If you need to take more than two additional doses to control your nausea or vomiting, contact your healthcare professional as you may need a higher dose or a different medicine.
Metoclopramide tablets: 20mg three times a day
Metoclopramide 10mg tablets
Take two tablets three times a day.
Supply 42 tablets.
Age: from 16 years onwards
NHS cost: £0.60
Licensed use: no - off-label dose
Metoclopramide subcutaneous inj: 10mg three times a day
Metoclopramide 10mg/2ml solution for injection ampoules
FOR SUBCUTANEOUS INJECTION. Give 2ml (10mg) three times a day.
Supply 10 2ml ampoules.
Age: from 16 years onwards
NHS cost: £2.60
Licensed use: no
Metoclopramide subcutaneous infusion: 30-100mg over 24 hours
Metoclopramide 10mg/2ml solution for injection ampoules
FOR CONTINUOUS SUBCUTANEOUS INFUSION. Give 6ml (30mg) to 20ml (100mg) over 24 hours via a syringe driver.
Supply 20 2ml ampoules.
Age: from 16 years onwards
NHS cost: £5.20
Licensed use: no
Domperidone tablets: 10-20mg every 6-8 hours
Domperidone 10mg tablets
Take one to two tablets every 6 to 8 hours when required for relief of nausea and vomiting. Do not take more than 8 tablets in 24 hours.
Supply 30 tablets.
Age: from 16 years onwards
NHS cost: £2.10
Licensed use: yes
Domperidone suppositories: 30-60mg every 4-8 hours
Domperidone 30mg suppositories
Insert one to two suppositories into the rectum every 4 to 8 hours when required for relief of nausea and vomiting. Do not use more than 4 suppositories in 24 hours.
Supply 20 suppositories.
Age: from 16 years onwards
NHS cost: £6.36
Licensed use: yes

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