CKS is no longer commissioned by the National Institute for Health and Clinical Excellence (NICE). NICE remains committed to providing a replacement service for CKS and is currently reviewing its options. In the meantime, although CKS content is now not being maintained, it still remains relevant and will continue to be made available. CKS content was generated under a programme of topic creation and update. To check if the topic you are viewing is current or out of date, please refer to the topic publication details by clicking on the 'How up-to-date is this topic?' link in the left hand menu on individual topic pages.
Palliative cancer care - oral problems - Management
What drug interactions occur with nystatin?
- As nystatin is not absorbed via the gastrointestinal tract when given orally, systemic drug interactions are unlikely.
- However, the combined use of nystatin and chlorhexidine mouthwash is not recommended because they will inactivate each other [Ellepola and Samaranayake, 2001]. They should be used 1 hour apart. Also, note that the use of chlorhexidine should not be used for 30 minutes after the use of toothpaste [Kinley, Personal Communication, 2007].
© NHS Institute for Innovation and Improvement