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Polycystic ovary syndrome - Management
Basis for recommendation
Screening for gestational diabetes
- These recommendations are based on guidance from the Royal College of Obstetricians and Gynaecologists. Good evidence from a meta-analysis suggests that women with PCOS have an increased risk of gestational diabetes mellitus.
Pregnancy complications
- Good evidence from a meta-analysis suggests that women with PCOS have an increased risk of pregnancy-induced hypertension, pre-eclampsia, and pre-term birth, and that the baby is at increased risk of neonatal complications.
Spontaneous miscarriage after assisted reproduction
- There is evidence that women with PCOS have a higher rate of spontaneous miscarriage after assisted reproduction.
Use of metformin
- The use of metformin in pregnancy is not recommended in guidelines from the Royal College of Obstetricians and Gynaecologists [RCOG, 2007] until further randomized prospective trials are available to provide adequate evidence of safety and efficacy.
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