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Prostatitis - acute - Evidence
Evidence on antibiotic treatment for acute prostatitis

There is no evidence from controlled clinical trials for the use of quinolones or trimethoprim to treat acute prostatitis.

CKS found one controlled trial of antibiotics used to treat acute acute prostatitis.

  • This trial compared outcomes in nine men with acute prostatitis and 79 men with chronic prostatitis who were treated with either minocycline or cefalexin [Paulson et al, 1986].
    • Results were reported for only 51% (44) of the participants.
    • At the 6-week follow up, clinical cure or improvement without recurrence was reported in 65% of the men taking minocycline and 46% of the men taking cefalexin.

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