Print Print
CKS is no longer commissioned by the National Institute for Health and Clinical Excellence (NICE). NICE remains committed to providing a replacement service for CKS and is currently reviewing its options. In the meantime, although CKS content is now not being maintained, it still remains relevant and will continue to be made available. CKS content was generated under a programme of topic creation and update. To check if the topic you are viewing is current or out of date, please refer to the topic publication details by clicking on the 'How up-to-date is this topic?' link in the left hand menu on individual topic pages.

Pruritus vulvae - Management
How should I manage pruritus vulvae caused by a possible neoplasm?

  • Refer urgently (within 2 weeks) all women with an unexplained vulval lump or ulcer.
    • If the woman presents with vulval pruritus or pain, but no other specific features, it is reasonable to use a period of 'treat, watch, and wait' as initial management. The woman should be followed up until symptoms resolve or a diagnosis is confirmed. If symptoms persist, refer with urgency depending on the symptoms and degree of concern about cancer.
      • Vulval intraepithelial neoplasia — a skin biopsy is required to confirm the diagnosis and pick up any early cancers. As 50% of women have associated abnormalities including cervical intraepithelial neoplasia or cancer, it is very important to have annual cervical smears.
      • Usually all vulval intraepithelial neoplasia lesions are treated to reduce the risk of cancer (in secondary care). Treatments which may be offered include removal of affected tissue, topical imiquimod, or 5-fluorouracil.

© NHS Institute for Innovation and Improvement