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Smoking cessation - Management
Which dose of bupropion should I prescribe?
- The recommended treatment dose is 150 mg once a day for 6 days, increasing to 150 mg twice a day (doses at least 8 hours apart).
- Continue the lower dose of 150 mg once a day if the person:
- Is older than 65 years of age.
- Has hepatic impairment (mild to moderate).
- Has renal impairment (glomerular filtration rate < 50 mL/min) [Ashley and Currie, 2004].
- Advise the person to stop smoking 7–14 days after starting bupropion.
[ABPI Medicines Compendium, 2006]
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