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Smoking cessation - Management
How should I stop bupropion?
- After a usual course of 7–9 weeks, discontinuation reactions are unlikely and bupropion can be stopped without tapering the dose.
- Because bupropion inhibits serotonin, there is a theoretical possibility that people on longer courses (typically 6 months or more) may experience a discontinuation reaction similar to people who discontinue antidepressants. Expert reviewers agree that this is very unusual, but if the person prefers, the dose could be halved 1–2 weeks before stopping.
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