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Smoking cessation - Management
Which dose of bupropion should I prescribe?
- The recommended treatment dose is 150 mg once a day for 6 days, increasing to 150 mg twice a day (doses at least 8 hours apart).
- Continue the lower dose of 150 mg once a day if the person:
- Is older than 65 years of age.
- Has hepatic impairment (mild to moderate).
- Has renal impairment (glomerular filtration rate < 50 mL/min).
- Advise the person to stop smoking 7–14 days after starting bupropion.
- The recommended course of treatment is 7–9 weeks.
- After a usual course of 7–9 weeks, bupropion can be stopped without tapering the dose. If the course of bupropion has been longer than 6 months, consider a tapering period.
In depth
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