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Stroke and transient ischaemic attack - Management
What drug interactions should I be aware of with clopidogrel?
- Avoid the concomitant use of clopidogrel and warfarin as this may increase the intensity of bleeding.
- Risk of bleeding is increased when clopidogrel is combined with:
- Aspirin.
- Nonsteroidal anti-inflammatory drugs: increased risk of gastrointestinal bleeding.
- Other drugs known to increase bleeding (e.g. glycoprotein IIb/IIIa inhibitors, heparin, and thrombolytics).
[ABPI Medicines Compendium, 2007a]
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