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Urinary tract infection - children - Management
What issues should I consider before prescribing trimethoprim?

  • Trimethoprim is available as a sugar-free suspension (50 mg/5 mL) or tablets (100 and 200 mg), and is licensed for children 6 weeks of age or older.
  • Trimethoprim is suitable for most children:
    • Trimethoprim may accumulate in the body of children with renal impairment. Use a different antibiotic or seek specialist advice about reducing the dose.
    • Trimethoprim has the potential to interact with several drugs, including amiodarone, phenytoin, and ciclosporin. If the child is receiving one of these drugs for a chronic condition, it is advisable to use an alternative antibiotic.

[BNF 54, 2007]

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