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Urinary tract infection (lower) - women - Management
What issues should I consider when prescribing ibuprofen?
- For a detailed discussion of the contraindications, adverse effects, monitoring issues, and interactions of nonsteroidal anti-inflammatory drugs (NSAIDs), see the CKS topic on NSAIDs - prescribing issues.
- Ibuprofen is generally the preferred NSAID because of its lower risk of gastrointestinal adverse effects [CSM, 2002].
- As with other NSAIDs, ibuprofen may worsen or precipitate gastrointestinal haemorrhage, asthma, hypertension, renal impairment, or cardiac failure. Avoid ibuprofen if there is a history of peptic ulcer.
- For use in women who are pregnant or breastfeeding, see Choice in pregnancy or breastfeeding.
- Ibuprofen and other NSAIDs are known to interact with ciclosporin, lithium, and methotrexate. NSAIDs should be initiated with caution in people taking these drugs. Consider seeking specialist advice.
- For people with epilepsy who are taking an NSAID, it may be best to avoid the concomitant use of a quinolone. For further information, see the section on Quinolone and an NSAID in the CKS topic on NSAIDs - prescribing issues.
[Aronson, 2006a; BNF 57, 2009]
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